[PDF][PDF] A comprehensive pan-cancer molecular study of gynecologic and breast cancers

AC Berger, A Korkut, RS Kanchi, AM Hegde, W Lenoir… - Cancer cell, 2018 - cell.com
We analyzed molecular data on 2,579 tumors from The Cancer Genome Atlas (TCGA) of
four gynecological types plus breast. Our aims were to identify shared and unique molecular …

Pan-cancer molecular classes transcending tumor lineage across 32 cancer types, multiple data platforms, and over 10,000 cases

F Chen, Y Zhang, DL Gibbons, B Deneen… - Clinical Cancer …, 2018 - AACR
Abstract Purpose: The Cancer Genome Atlas data resources represent an opportunity to
explore commonalities across cancer types involving multiple molecular levels, but tumor …

[HTML][HTML] UALCAN: a portal for facilitating tumor subgroup gene expression and survival analyses

DS Chandrashekar, B Bashel, SAH Balasubramanya… - Neoplasia, 2017 - Elsevier
Abstract Genomics data from The Cancer Genome Atlas (TCGA) project has led to the
comprehensive molecular characterization of multiple cancer types. The large sample …

A comprehensive genomic pan-cancer classification using The Cancer Genome Atlas gene expression data

Y Li, K Kang, JM Krahn, N Croutwater, K Lee… - BMC genomics, 2017 - Springer
Abstract Background The Cancer Genome Atlas (TCGA) has generated comprehensive
molecular profiles. We aim to identify a set of genes whose expression patterns can …

PanCancer insights from The Cancer Genome Atlas: the pathologist's perspective

LAD Cooper, EG Demicco, JH Saltz… - The Journal of …, 2018 - Wiley Online Library
Abstract The Cancer Genome Atlas (TCGA) represents one of several international consortia
dedicated to performing comprehensive genomic and epigenomic analyses of selected …

[PDF][PDF] Perspective on oncogenic processes at the end of the beginning of cancer genomics

L Ding, MH Bailey, E Porta-Pardo, V Thorsson… - Cell, 2018 - cell.com
Summary The Cancer Genome Atlas (TCGA) has catalyzed systematic characterization of
diverse genomic alterations underlying human cancers. At this historic junction marking the …

Insight into the heterogeneity of breast cancer through next-generation sequencing

HG Russnes, N Navin, J Hicks… - The Journal of …, 2011 - Am Soc Clin Investig
Rapid and sophisticated improvements in molecular analysis have allowed us to sequence
whole human genomes as well as cancer genomes, and the findings suggest that we may …

[PDF][PDF] A multi-omic single-cell landscape of human gynecologic malignancies

MJ Regner, K Wisniewska, S Garcia-Recio… - Molecular cell, 2021 - cell.com
Deconvolution of regulatory mechanisms that drive transcriptional programs in cancer cells
is key to understanding tumor biology. Herein, we present matched transcriptome (scRNA …

Integrated proteogenomic characterization of human high-grade serous ovarian cancer

H Zhang, T Liu, Z Zhang, SH Payne, B Zhang… - Cell, 2016 - cell.com
To provide a detailed analysis of the molecular components and underlying mechanisms
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …

A pathology atlas of the human cancer transcriptome

M Uhlen, C Zhang, S Lee, E Sjöstedt, L Fagerberg… - Science, 2017 - science.org
INTRODUCTION Cancer is a leading cause of death worldwide, and there is great need to
define the molecular mechanisms driving the development and progression of individual …