Silica-based nanoparticles for biomedical applications: from nanocarriers to biomodulators

Y Yang, M Zhang, H Song, C Yu - Accounts of chemical research, 2020 - ACS Publications
Conspectus Silica-based nanoparticles (SNPs) are a classic type of material employed in
biomedical applications because of their excellent biocompatibility and tailorable …

[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers

TI Janjua, Y Cao, F Kleitz, M Linden, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

Key parameters for the rational design, synthesis, and functionalization of biocompatible mesoporous silica nanoparticles

M Florensa, M Llenas, E Medina-Gutiérrez, S Sandoval… - Pharmaceutics, 2022 - mdpi.com
Over the last few years, research on silica nanoparticles has rapidly increased. Particularly
on mesoporous silica nanoparticles (MSNs), as nanocarriers for the treatment of various …

[HTML][HTML] An update on mesoporous silica nanoparticle applications in nanomedicine

E Rastegari, YJ Hsiao, WY Lai, YH Lai, TC Yang… - Pharmaceutics, 2021 - mdpi.com
The efficient and safe delivery of therapeutic drugs, proteins, and nucleic acids are essential
for meaningful therapeutic benefits. The field of nanomedicine shows promising implications …

Multifunctional silica nanoparticles as a promising theranostic platform for biomedical applications

Z Xu, X Ma, YE Gao, M Hou, P Xue, CM Li… - Materials chemistry …, 2017 - pubs.rsc.org
Theranostic nanoplatforms represent an important tool in the diagnosis and therapy of many
major diseases, especially in the field of cancer theranostics, for which a myriad of …

Mesoporous silica nanoparticles: a multifunctional nano therapeutic system

WX Mai, H Meng - Integrative Biology, 2013 - academic.oup.com
Efficient and safe drug delivery has always been a challenge in medicine. The use of
nanotechnology, such as the development of nano drug delivery systems (DDS), has …

Understanding the mechanisms of silica nanoparticles for nanomedicine

Z Li, Y Mu, C Peng, MF Lavin… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
As a consequence of recent progression in biomedicine and nanotechnology,
nanomedicine has emerged rapidly as a new discipline with extensive application of …

Nanosilica: Recent progress in synthesis, functionalization, biocompatibility, and biomedical applications

P Singh, S Srivastava, SK Singh - ACS Biomaterials Science & …, 2019 - ACS Publications
Silica nanoparticles (Si-NPs) are widely explored in biomedical applications due to their
high surface area, excellent biocompatibility, and tunable pore size. The silica surface can …

Silica nanoparticles as a delivery system for nucleic acid-based reagents

C Hom, J Lu, F Tamanoi - Journal of materials chemistry, 2009 - pubs.rsc.org
The transport of nucleic acid-based reagents is predicated upon developing structurally
stable delivery systems that can preferentially bind and protect DNA and RNA, and release …

Silica-based multifunctional nanodelivery systems toward regenerative medicine

RA Perez, RK Singh, TH Kim, HW Kim - Materials Horizons, 2017 - pubs.rsc.org
Silica-based nanomaterials (SiNMs) with different forms, including nanoparticles, nanorods
and nanofibers either with a dense, porous or hollow structure, have been demonstrated as …