Background Rectal cancers represent 35% of colorectal cancers; 90% are
adenocarcinomas, while squamous cell carcinoma accounts for 0.3% of them. Given its …

Background Squamous cell cancers of the anal canal (ASCC) are increasing in frequency
and lack effective therapies for advanced disease. Although an association with human …

Anal squamous cell carcinomas (ASCC) are rare tumours in humans. The etiological role of
HPV infection is now well established but little is known about the molecular landscape and …

Background Overall declines in incidence of rectal cancer (RC) in patients older than 50
years have been mostly attributed to improvement in treatment modalities and introduction of …

Squamous cell carcinoma of the anal canal (SCCA) is a rare gastrointestinal malignancy
with an increasing annual incidence globally. The majority of cases are linked to prior …

Genomic alterations of anal squamous cell carcinoma (ASCC) remain poorly understood
due to the rarity of this tumor. Array comparative genomic hybridization and targeted gene …

Anal squamous cell carcinoma (ASCC) is a rare tumor of the gastrointestinal tract. We aimed
to compare the genetic backgrounds and their effect on clinical outcomes between …

Purpose. Human papillomavirus (HPV) antigens had been found in colorectal cancer (CRC)
tissue, but little evidence demonstrates the association of HPV with oncogene mutations in …

Squamous cell carcinoma (SqCC) is the most common malignancy of the anal canal, where
it is strongly associated with HPV infection. Characteristic genomic alterations have been …

Colorectal cancer (CRC) is a common cancer globally. It is a complex disease influenced by
genetic and environmental factors. Early studies on familial cases have identified major …