The gut microbiome in hypertension: recent advances and future perspectives

EG Avery, H Bartolomaeus, A Maifeld, L Marko… - Circulation …, 2021 - Am Heart Assoc
The pathogenesis of hypertension is known to involve a diverse range of contributing factors
including genetic, environmental, hormonal, hemodynamic and inflammatory forces, to …

The gut microbiome and hypertension

M Pevsner-Fischer, E Blacher… - Current opinion in …, 2017 - journals.lww.com
In this review, we discuss the accumulating research pointing to possible interplays between
the gut microbiome and hypertension and highlight future prospects by which utilization of …

Microbiome and hypertension: where are we now?

NG Vallianou, E Geladari… - Journal of Cardiovascular …, 2020 - journals.lww.com
Background Hypertension is the leading risk factor for cardiovascular disease and accounts
for approximately 9.4 million deaths globally every year. Hypertension is a complex entity …

The gut microbiome and hypertension

JA O'Donnell, T Zheng, G Meric… - Nature Reviews …, 2023 - nature.com
A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …

Impaired autonomic nervous system-microbiome circuit in hypertension: a premise for hypertension therapy

J Zubcevic, EM Richards, T Yang, S Kim… - Circulation …, 2019 - Am Heart Assoc
Hypertension affects an estimated 103 million Americans, yet gaps in knowledge continue to
limit its successful management. Rapidly emerging evidence is linking gut dysbiosis to many …

Alterations of the gut microbiome in hypertension

Q Yan, Y Gu, X Li, W Yang, L Jia, C Chen… - Frontiers in cellular …, 2017 - frontiersin.org
Introduction: Human gut microbiota is believed to be directly or indirectly involved in
cardiovascular diseases and hypertension. However, the identification and functional status …

Gut microbiome and neuroinflammation in hypertension

EM Richards, J Li, BR Stevens, CJ Pepine… - Circulation …, 2022 - Am Heart Assoc
Hypertension is a worldwide problem with major impacts on health including morbidity and
mortality, as well as consumption of health care resources. Nearly 50% of American adults …

The effect of diet on hypertensive pathology: is there a link via gut microbiota-driven immunometabolism?

HA Jama, A Beale, WA Shihata… - Cardiovascular …, 2019 - academic.oup.com
Over the past decade, the immune system has emerged as an important component in the
aetiology of hypertension. There has been a blooming interest in the contribution of the gut …

Role of the microbiota in hypertension and antihypertensive drug metabolism

E Mishima, T Abe - Hypertension Research, 2022 - nature.com
Recent evidence suggests that the gut microbiota plays an important role in the
development and pathogenesis of hypertension. Dysbiosis, an imbalance in the composition …

Gut microbiota and hypertension: From pathogenesis to new therapeutic strategies

Y Kang, Y Cai - Clinics and research in hepatology and …, 2018 - Elsevier
Hypertension (HTN) has become a global public health concern and a major risk factor for
cardiovascular, cerebrovascular, and kidney diseases. The complex interplay of genetic and …