[HTML][HTML] Neutrophil membrane-camouflaged nanoparticles alleviate inflammation and promote angiogenesis in ischemic myocardial injury

D Han, F Wang, Z Qiao, B Wang, Y Zhang, Q Jiang… - Bioactive Materials, 2023 - Elsevier
Acute myocardial infarction (AMI) induces a sterile inflammatory response, leading to
cardiomyocyte damage and adverse cardiac remodeling. Interleukin-5 (IL-5) plays an …

[HTML][HTML] Targeted neutrophil-mimetic liposomes promote cardiac repair by adsorbing proinflammatory cytokines and regulating the immune microenvironment

J Chen, Y Song, Q Wang, Q Li, H Tan, J Gao… - Journal of …, 2022 - Springer
Acute myocardial infarction (MI) induces a sterile inflammatory response that may result in
poor cardiac remodeling and dysfunction. Despite the progress in anti-cytokine biologics …

[HTML][HTML] Designer functional nanomedicine for myocardial repair by regulating the inflammatory microenvironment

C Liu, Z Fan, D He, H Chen, S Zhang, S Guo, B Zheng… - Pharmaceutics, 2022 - mdpi.com
Acute myocardial infarction is a major global health problem, and the repair of damaged
myocardium is still a major challenge. Myocardial injury triggers an inflammatory response …

Engineered macrophage membrane‐enveloped nanomedicine for ameliorating myocardial infarction in a mouse model

Y Xue, G Zeng, J Cheng, J Hu… - Bioengineering & …, 2021 - Wiley Online Library
Myocardial infarction (MI) is the serious condition causing lots of death over the world.
Myocytes apoptosis, inflammation, and fibrosis are three important factors implicated in …

[HTML][HTML] Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolution

L Bao, G Dou, R Tian, Y Lv, F Ding, S Liu, R Zhao… - Bioactive materials, 2022 - Elsevier
Inflammatory response plays a critical role in myocardial infarction (MI) repair. The
neutrophil apoptosis and subsequent macrophage ingestion can result in inflammation …

Engineered nanoparticles disguised as macrophages for trapping lipopolysaccharide and preventing endotoxemia

S Shen, F Han, A Yuan, L Wu, J Cao, J Qian, X Qi… - Biomaterials, 2019 - Elsevier
Endotoxemia is a severe pathophysiology induced by bacterial endotoxin (also known as
lipopolysaccharide, LPS), causing high mortality in clinic due to the life-threatening …

Promoting cardiac repair through simple engineering of nanoparticles with exclusive targeting capability toward myocardial reperfusion injury by thermal resistant …

Z Liu, W Lian, Q Long, R Cheng… - Advanced Functional …, 2022 - Wiley Online Library
Nanoparticle (NP)‐based intravenous administration represents the most convenient
cardiac targeting delivery routine, yet, there are still therapeutic issues due to the lack of …

Endothelial cell-targeting, ROS-ultrasensitive drug/siRNA co-delivery nanocomplexes mitigate early-stage neutrophil recruitment for the anti-inflammatory treatment of …

M Hou, X Wu, Z Zhao, Q Deng, Y Chen, L Yin - Acta Biomaterialia, 2022 - Elsevier
Neutrophils serve as a key contributor to the pathophysiology of myocardial ischemia
reperfusion injury (MIRI), because the unregulated activation and infiltration of neutrophils …

Targeted Delivery of Apoptotic Cell‐Derived Nanovesicles prevents Cardiac Remodeling and Attenuates Cardiac Function Exacerbation

JR Lee, WS Sim, HJ Park, BW Park… - Advanced Functional …, 2023 - Wiley Online Library
The modulation of inflammatory responses plays an important role in the pathobiology of
cardiac failure. In a natural healing process, the ingestion of apoptotic cells and their …

Bioinspired macrophage-targeted anti-inflammatory nanomedicine: A therapeutic option for the treatment of myocarditis

R Toita, T Kawano, M Murata, JH Kang - Materials Science and …, 2021 - Elsevier
Myocarditis is a disease characterized by inflammation of the heart muscle, which increases
the risk of dilated cardiomyopathy and heart failure. Macrophage migration is a major …