Triglyceride-rich lipoproteins as a causal factor for cardiovascular disease

PP Toth - Vascular health and risk management, 2016 - Taylor & Francis
Approximately 25% of US adults are estimated to have hypertriglyceridemia (triglyceride
[TG] level≥ 150 mg/dL [≥ 1.7 mmol/L]). Elevated TG levels are associated with increased …

Genetics and causality of triglyceride-rich lipoproteins in atherosclerotic cardiovascular disease

RS Rosenson, MH Davidson, BJ Hirsh… - Journal of the American …, 2014 - jacc.org
Triglycerides represent 1 component of a heterogeneous pool of triglyceride-rich
lipoproteins (TGRLs). The reliance on triglycerides or TGRLs as cardiovascular disease …

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

MJ Chapman, HN Ginsberg, P Amarenco… - European heart …, 2011 - academic.oup.com
Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic
abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically …

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus …

HN Ginsberg, CJ Packard, MJ Chapman… - European heart …, 2021 - academic.oup.com
Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …

[HTML][HTML] Triglyceride-rich lipoproteins and remnant cholesterol in Cardiovascular Disease

JH Heo, SH Jo - Journal of Korean medical science, 2023 - synapse.koreamed.org
Despite the well-established benefits of statin treatments in lowering low-density lipoprotein
cholesterol (LDL-C), a significant residual risk for atherosclerotic cardiovascular disease …

Triglycerides: a risk factor for coronary heart disease

J Davignon, JS Cohn - Atherosclerosis, 1996 - Elsevier
Multivariate analysis of epidemiological data has often shown that elevated plasma
triglyceride (TG) concentration is not an independent risk factor for coronary heart disease …

[HTML][HTML] Triglyceride and triglyceride-rich lipoproteins in atherosclerosis

BH Zhang, F Yin, YN Qiao, SD Guo - Frontiers in Molecular …, 2022 - frontiersin.org
Cardiovascular disease (CVD) is still the leading cause of death globally, and
atherosclerosis is the main pathological basis of CVDs. Low-density lipoprotein cholesterol …

The role of triglycerides in atherosclerosis

BG Talayero, FM Sacks - Current cardiology reports, 2011 - Springer
Hypertriglyceridemia is a prevalent risk factor for cardiovascular disease (CVD) and
increasingly important in the setting of current obesity and insulin resistance epidemics …

Triglyceride-rich lipoproteins and atherosclerotic cardiovascular disease: new insights from epidemiology, genetics, and biology

BG Nordestgaard - Circulation research, 2016 - Am Heart Assoc
Scientific interest in triglyceride-rich lipoproteins has fluctuated over the past many years,
ranging from beliefs that these lipoproteins cause atherosclerotic cardiovascular disease …

Triglyceride-rich lipoprotein remnants, low-density lipoproteins, and risk of coronary heart disease: a UK Biobank study

E Björnson, M Adiels, MR Taskinen… - European Heart …, 2023 - academic.oup.com
Aims The strength of the relationship of triglyceride-rich lipoproteins (TRL) with risk of
coronary heart disease (CHD) compared with low-density lipoprotein (LDL) is yet to be …