Researches and applications of stem cell secretome

J Xia, S Arai, KH Haider - Stem cells: from potential to promise, 2021 - Springer
Unlike the terminally differentiated somatic cells, stem cells are characterized by their
unlimited, undifferentiated self-renewal, and differentiation potential to adopt diverse …

Stem cell secretome as a new booster for regenerative medicine

J Xia, S Minamino, K Kuwabara, S Arai - Bioscience Trends, 2019 - jstage.jst.go.jp
Stem cells are an undifferentiated cell population that has the ability to develop into many
different cell types and also has the ability to repair damaged tissues in some cases. For a …

Comparing the therapeutic potential of stem cells and their secretory products in regenerative medicine

JB Foo, QH Looi, PP Chong, NH Hassan… - Stem cells …, 2021 - Wiley Online Library
Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …

tissue repair and regenerative mechanisms by stem/progenitor cells and their secretome

R Gramignoli, F Sallustio, D Widera… - Frontiers in Medicine, 2019 - frontiersin.org
Regenerative medicine is a branch of translational research which is energizing and
empowering clinical practice. A multitude of novel approaches proposed during the recent …

[HTML][HTML] Mesenchymal stem cells secretome: The cornerstone of cell-free regenerative medicine

A González-González, D García-Sánchez… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are the most frequently used stem cells in clinical trials due
to their easy isolation from various adult tissues, their ability of homing to injury sites and …

Stem cells as drug delivery methods: application of stem cell secretome for regeneration

C Tran, MS Damaser - Advanced drug delivery reviews, 2015 - Elsevier
Mesenchymal stem cells (MSCs) are a unique cell population defined by their ability to
indefinitely self-renew, differentiate into multiple cell lineages, and form clonal cell …

Secretome: pharmaceuticals for cell-free regenerative therapy

N Haque, BJJ Abdullah, NHA Kasim - Stem Cell Drugs-A New Generation …, 2018 - Springer
Stem cells are currently considered to be the best tool for regenerative medicine because of
their self-renewal capability and plasticity. It was assumed that the outcomes of cell-based …

Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?

FG Teixeira, MM Carvalho, N Sousa… - Cellular and Molecular …, 2013 - Springer
The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …

Biological activity of mesenchymal stem cells secretome as a basis for cell-free therapeutic approach

LA Pokrovskaya, EV Zubareva… - Research Results in …, 2020 - cyberleninka.ru
Mesenchymal stem (stromal) cells (MSCs) are self-renewing, cultured adult stem cells which
secrete a complex set of multiple soluble biologically active molecules such as chemokines …

Molecular mechanisms responsible for therapeutic potential of mesenchymal stem cell-derived secretome

CR Harrell, C Fellabaum, N Jovicic, V Djonov… - Cells, 2019 - mdpi.com
Mesenchymal stem cell (MSC)-sourced secretome, defined as the set of MSC-derived
bioactive factors (soluble proteins, nucleic acids, lipids and extracellular vesicles), showed …