Epigenetics in prostate cancer: biologic and clinical relevance

C Jerónimo, PJ Bastian, A Bjartell, GM Carbone… - European urology, 2011 - Elsevier
CONTEXT: Prostate cancer (PCa) is one of the most common human malignancies and
arises through genetic and epigenetic alterations. Epigenetic modifications include DNA …

Epigenetic biomarkers in prostate cancer: Current and future uses

K Chiam, C Ricciardelli, T Bianco-Miotto - Cancer letters, 2014 - Elsevier
Epigenome alterations are characteristic of nearly all human malignancies and include
changes in DNA methylation, histone modifications and microRNAs (miRNAs). However …

Epigenetic modifications in prostate cancer

M Sugiura, H Sato, M Kanesaka… - … Journal of Urology, 2021 - Wiley Online Library
Prostate cancer is a major cause of cancer‐related deaths among men worldwide. In
addition to genomic alterations, epigenetic alterations accumulated in prostate cancer have …

Epigenetic changes in prostate cancer: implication for diagnosis and treatment

LC Li, PR Carroll, R Dahiya - Journal of the National Cancer …, 2005 - academic.oup.com
Prostate cancer is the most common noncutaneous malignancy and the second leading
cause of cancer death among men in the United States. DNA methylation and histone …

Aberrant DNA methylation and prostate cancer

S Majumdar, E Buckles, J Estrada… - Current …, 2011 - ingentaconnect.com
Prostate cancer (PCa) is the most prevalent cancer, a significant contributor to morbidity and
a leading cause of cancer-related death in men in Western industrialized countries. In …

DNA methylation and histone modifications as epigenetic regulation in prostate cancer

M Nowacka-Zawisza, E Wiśnik - Oncology reports, 2017 - spandidos-publications.com
Prostate cancer is the second most commonly diagnosed cancer in men in Poland after lung
cancer and the third leading cause of cancer-related mortality after lung and colon cancer …

Epigenetic modifications in prostate cancer

M Ngollo, A Dagdemir, S Karsli-Ceppioglu, G Judes… - …, 2014 - Taylor & Francis
Prostate cancer is the most common cancer in men and the second leading cause of cancer
deaths in men in France. Apart from the genetic alterations in prostate cancer, epigenetics …

Epigenetics of prostate cancer: beyond DNA methylation

WA Schulz, J Hatina - Journal of cellular and molecular …, 2006 - Wiley Online Library
Epigenetic mechanisms permit the stable inheritance of cellular properties without changes
in DNA sequence or amount. In prostate carcinoma, epigenetic mechanisms are essential …

The epigenome as a therapeutic target in prostate cancer

AS Perry, RWG Watson, M Lawler… - Nature Reviews …, 2010 - nature.com
During cancer development and progression, tumor cells undergo abnormal epigenetic
modifications, including DNA methylation, histone deacetylation and nucleosome …

Recent advances in epigenetic biomarkers and epigenetic targeting in prostate cancer

A Kumaraswamy, KRW Leng, TC Westbrook, JA Yates… - European urology, 2021 - Elsevier
Context In addition to genetic alterations, epigenetic alterations play a crucial role during
prostate cancer progression. A better understanding of the epigenetic factors that promote …