Comparison of pharmacokinetic properties of beta-adrenoceptor blocking drugs

DG McDevitt - European heart journal, 1987 - academic.oup.com
Beta-adrenoceptor blocking drugs can be characterised by their pharmacokinetic properties.
One of the most important factors appears to be lipid solubility. Lipophilic beta-adrenoceptor …

Clinical pharmacokinetics of β-adrenoceptor antagonists: an update

JG Riddell, DWG Harron, RG Shanks - Clinical pharmacokinetics, 1987 - Springer
The β-adrenoceptor antagonists have been widely used clinically for over 20 years and their
pharmacokinetics have been more thoroughly investigated than any other group of drugs …

Pharmacokinetics of beta-adrenoceptor blocking agents: clinical significance of hepatic and/or renal clearance.

U Borchard - Clinical physiology and biochemistry, 1990 - europepmc.org
A great number of beta-adrenoceptor blocking drugs are now available for clinical use which
show great differences with respect to their pharmacokinetic properties. Bioavailability might …

Clinical pharmacokinetics of β-adrenoceptor blocking drugs

G Johnsson, CG Regårdh - Clinical pharmacokinetics, 1976 - Springer
All β-adrenoreceptor blocking drugs seem to be fairly rapidly and completely absorbed from
the gastro-intestinal tract. The rate of absorption, however, appears to be lower in elderly …

Pharmacokinetic comparison of pindolol with other beta-adrenoceptor-blocking agents

J Meier - American Heart Journal, 1982 - Elsevier
Many beta-adrenoceptor-blocking agents are well studied today. They difer from one
another not only in their pharmacologic profiles (cardioselectivity, intrinsic sympathomimetic …

[PDF][PDF] β-adrenoceptor-blocking agents: pharmacokinetic differences and their clinical implications illustrated on pindolol

J Meier - Cardiology, 1979 - karger.com
Quite a number of j3-adrenoceptor-blocking drugs are available today for the treatment of
hypertension and other cardiovascular disorders. Since ß-blockers are drugs which are …

The additional properties of beta adrenoceptor blocking drugs

BNC Prichard, B Tomlinson - Journal of Cardiovascular …, 1986 - journals.lww.com
Beta adrenoceptor blocking drugs are all competitive inhibitors of the beta receptor although
they may or may not possess, beta 1-(cardio) selectivity, intrinsic sympathomimetic activity …

Pharmacokinetic optimisation of therapy with β-adrenergic blocking agents

WH Frishman, EJ Lazar, G Gorodokin - Clinical pharmacokinetics, 1991 - Springer
Summary β-Adrenergic blockade has provided one of the major pharmacotherapeutic
advances of this century. The drugs in this class have the common property of blocking the …

[引用][C] An investigation of the comparative liposolubilities of β-adrenoceptor blocking agents

PB Woods, ML Robinson - Journal of Pharmacy and …, 1981 - academic.oup.com
Currently there are nine 8-adrenoceptor blocking drugs and one a/,!?-blocker available for
clinical use in the UK The pharmacokinetics of the group vary significantly from one member …

[PDF][PDF] Pharmacological properties of beta-adrenoceptor blocking drugs

U Borchard - Journal of Clinical and Basic Cardiology, 1998 - kup.at
J Clin Bas Cardiol 1998; 1: 5 β-adrenoceptor blocking drugs are widely used for the
treatment of cardiovascular diseases such as arterial hypertension, coronary heart disease …