Objective: To test the efficacy of an animal model of pain and stress and evaluate the effects
of celecoxib administered when orthodontic force is applied. Materials and Methods: A 20-g …

In a previous study, we reported that the short-term treatment with celecoxib, a non-steroidal
anti-inflammatory drug (NSAID) attenuates the activation of brain structures related to …

Objective: To test the hypothesis that short-and long-term celecoxib administration has no
effect on orthodontic tooth movement. Materials and Methods: Male Wistar rats were …

Non-steroidal anti-inflammatory drugs (NSAIDs) have been used for pain relief in
orthodontics, but clinical studies reported that they may reduce tooth movement (TM). By …

Anti-inflammatory substances used for treatment of pain and discomfort related to
orthodontic treatment (OT) could slow down tooth movement. Selective cyclooxygenase-2 …

Objective: To investigate by behavioral methods the relationship between emotional stress
and pain during experimental tooth movement in rats. Materials and Methods: Sixteen male …

Objective: To provide a semi-quantitative assessment of the effect of different analgesics
(celecoxib, ketorolac, and paracetamol) on tooth movement and bone resorption using …

Aim: To test whether orofacial mechanical and thermal hypersensitivities occur in rats during
orthodontic tooth movement (OTM). Methods: Sprague-Dawley rats (140 to 160 g) were …

Purpose: To evaluate the effect of a selective cyclooxygenase 2 (COX-2) inhibitor on
trigeminal ganglion changes and orofacial discomfort/nociception in rats submitted to an …

Objective: Inhibition of prostaglandin (PGs) production leads to decrease in orthodontic tooth
movement (OTM). It is not known whether inhibition of cyclooxygenase-1 (COX-1) or …