Construction of a macula-specific lncRNA-miRNA-mRNA network in age-related macular degeneration patients

S Chen, Y Chen, Z Yue, J Diao, F Tong, R Wei - 2022 - researchsquare.com
Background: Age-related macular degeneration (AMD) is the primary cause of visual
impairment among the elderly. It mainly affects the macular region of the fundus oculi …

[HTML][HTML] Identification of key lncRNAs in age-related macular degeneration through integrated bioinformatics and experimental validation

Y Ji, C Zuo, N Liao, L Yao, R Yang, H Chen… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
This study aimed to identify key long noncoding RNAs (lncRNAs) in age-related macular
degeneration (AMD) patients and to identify relevant pathological mechanisms of AMD …

Potential of long non-coding RNAs in age-related macular degeneration

J Blasiak, JMT Hyttinen, J Szczepanska… - International Journal of …, 2021 - mdpi.com
Age-related macular degeneration (AMD) is the leading cause of visual impairment in the
aging population with poorly known pathogenesis and lack of effective treatment. Age and …

Identification of lncRNAs involved in biological regulation in early age-related macular degeneration

W Zhu, YF Meng, Q Xing, JJ Tao, J Lu… - International Journal of …, 2017 - Taylor & Francis
Background Age-related macular degeneration (AMD) is one of the most common causes of
adult blindness in developed countries. However, the role of long noncoding RNAs …

Analysis of long noncoding RNAs in the aqueous humor of wet age-related macular degeneration

H Wang, C Wang, Y Yao, J Duan, Y Liang… - Experimental Eye …, 2023 - Elsevier
Wet age-related macular degeneration (wAMD) is the main cause of irreversible blindness
in the elderly, and its pathogenesis is still not fully understood. Long non-coding RNAs …

LINC00167 regulates RPE differentiation by targeting the miR-203a-3p/SOCS3 axis

X Chen, R Sun, D Yang, C Jiang, Q Liu - Molecular Therapy-Nucleic Acids, 2020 - cell.com
Increasing evidence has indicated that long non-coding RNAs (lncRNAs) play significant
roles in various diseases; however, their roles in age-related macular degeneration (AMD) …

The Potential Role of Genetic Variations in MicroRNA Binding Sites in Age-Related Macular Degeneration

N Popp, EY Chew, JJ Wang, P Mitchell… - … & Visual Science, 2014 - tvst.arvojournals.org
Purpose Age related macular degeneration (AMD) is a leading cause of irreversible central
vision loss in the elderly. Genetic factors contributing to AMD include single nucleotide …

Roles and mechanisms of long non-coding RNAs in age-related macular degeneration

R Zhang, L Wang, Y Li, C Gui, Y Pei, G Zhou - Heliyon, 2023 - cell.com
Worldwide, age-related macular degeneration (AMD) is a multifactorial progressive fundus
disorder that can cause vision impairment and severe central blindness in older adults …

[HTML][HTML] Identification and Validation of an Aging-Associated circRNA-miRNA-mRNA Network in Neovascular Age-Related Macular Degeneration

J Wu, Y Jiang, J Sun, X Sun - Gerontology, 2023 - karger.com
Introduction: Neovascular age-related macular degeneration (NVAMD) is a leading cause of
severe vision impairment in the elderly. Aging is one of the most pivotal underlying …

Integrated analysis of long non-coding RNA-mRNA profile and validation in diabetic cataract

X Han, L Cai, Y Shi, Z Hua, Y Lu, D Li… - Current eye research, 2022 - Taylor & Francis
Purpose To illustrate the expression profile of lncRNAs and mRNAs in diabetic cataract (DC)
and explore their potential role in the pathogenesis of DC. Methods LncRNA and mRNA …