Germline HABP2 Mutation Causing Familial Nonmedullary Thyroid Cancer
Familial nonmedullary thyroid cancer accounts for 3 to 9% of all cases of thyroid cancer, but
the susceptibility genes are not known. Here, we report a germline variant of HABP2 in …
the susceptibility genes are not known. Here, we report a germline variant of HABP2 in …
HABP2 Gene Mutations Do Not Cause Familial or Sporadic Non-Medullary Thyroid Cancer in a Highly Inbred Middle Eastern Population
Background: Familial non-medullary thyroid cancer (NMTC) occurs either as part of known
hereditary syndromes or as a non-syndromic isolated hereditary tumor. Although the genes …
hereditary syndromes or as a non-syndromic isolated hereditary tumor. Although the genes …
HABP2 G534E Mutation in Familial Nonmedullary Thyroid Cancer
T Zhang, M Xing - Journal of the National Cancer Institute, 2016 - academic.oup.com
Papillary thyroid cancer (PTC) is a common endocrine malignancy, accounting for nearly
90% of all thyroid cancers. About 5% of PTC is hereditary familial nonmedullary thyroid …
90% of all thyroid cancers. About 5% of PTC is hereditary familial nonmedullary thyroid …
HABP2 G534E Variant in Papillary Thyroid Carcinoma
J Tomsic, R Fultz, S Liyanarachchi, H He, L Senter… - PLoS …, 2016 - journals.plos.org
The main nonmedullary form of thyroid cancer is papillary thyroid carcinoma (PTC) that
accounts for 80–90% of all thyroid malignancies. Only 3–10% of PTC patients have a …
accounts for 80–90% of all thyroid malignancies. Only 3–10% of PTC patients have a …
The HABP2 G534E Variant Is an Unlikely Cause of Familial Nonmedullary Thyroid Cancer
R Sahasrabudhe, J Stultz, J Williamson… - The journal of …, 2016 - academic.oup.com
Context: A recent study reported the nonsynonymous G534E (rs7080536, allele A) variant in
the HABP2 gene as causal in familial nonmedullary thyroid cancer (NMTC). Objective: The …
the HABP2 gene as causal in familial nonmedullary thyroid cancer (NMTC). Objective: The …
HABP2 germline variants are uncommon in familial nonmedullary thyroid cancer
Background The genetic basis of nonsyndromic familial nonmedullary thyroid cancer
(FNMTC) is poorly understood. A recent study identified HABP2 as a tumor suppressor gene …
(FNMTC) is poorly understood. A recent study identified HABP2 as a tumor suppressor gene …
Familial non-medullary thyroid cancer: unraveling the genetic maze
SP Yang, J Ngeow - Endocrine-related cancer, 2016 - erc.bioscientifica.com
Familial non-medullary thyroid cancer (FNMTC) constitutes 3–9% of all thyroid cancers. Out
of all FNMTC cases, only 5% in the syndromic form has well-studied driver germline …
of all FNMTC cases, only 5% in the syndromic form has well-studied driver germline …
Familial thyroid cancer
O Alsanea, OH Clark - Current opinion in oncology, 2001 - journals.lww.com
Familial thyroid cancer can arise from parafollicular cells (familial medullary thyroid cancer)
or from follicular cells (familial nonmedullary thyroid cancer). Familial medullary thyroid …
or from follicular cells (familial nonmedullary thyroid cancer). Familial medullary thyroid …
Genetic predisposition to familial nonmedullary thyroid cancer: an update of molecular findings and state‐of‐the‐art studies
E Bonora, G Tallini, G Romeo - Journal of oncology, 2010 - Wiley Online Library
Familial thyroid cancer has become a well‐recognized entity in patients with thyroid cancer
originating from follicular cells, that is, nonmedullary thyroid carcinoma. The diagnosis of …
originating from follicular cells, that is, nonmedullary thyroid carcinoma. The diagnosis of …
Genetic predisposition for nonmedullary thyroid cancer
R Nagy, MD Ringel - Hormones and Cancer, 2015 - Springer
Nonmedullary thyroid cancer (NMTC) can be sporadic or can occur as a component cancer
as part of several well-described hereditary cancer syndromes. NMTC, particularly papillary …
as part of several well-described hereditary cancer syndromes. NMTC, particularly papillary …