The neural basis of abnormal social behavior in autism spectrum disorders (ASDs) remains
incompletely understood. Here we used two complementary but independent brain-wide …

Mouse models of neuropsychiatric diseases provide a platform for mechanistic
understanding and development of new therapies. We previously demonstrated that …

Alterations in the balance between neuronal excitation and inhibition (E: I balance) have
been implicated in the neural circuit activity–based processes that contribute to autism …

Social behaviors, how individuals act cooperatively and competitively with conspecifics, are
widely seen across species. Rodents display various social behaviors, and many different …

Autism spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs
new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti …

Autism spectrum disorders (ASD) form a heterogeneous, neurodevelopmental syndrome
characterized by deficits in social interactions and repetitive behavior/restricted interests …

Parallel processing circuits are thought to dramatically expand the network capabilities of
the nervous system. Magnocellular and parvocellular oxytocin neurons have been proposed …

Oxytocin (OT) has become a focus in investigations of autism spectrum disorder (ASD). The
social deficits that characterize ASD may relate to reduced connectivity between brain sites …

Functional connectivity aberrancies, as measured with resting-state functional magnetic
resonance imaging (rsfMRI), have been consistently observed in the brain of autism …

Loss-of-function mutations in CNTNAP2 cause a syndromic form of autism spectrum
disorder in humans and produce social deficits, repetitive behaviors, and seizures in mice …