New classes of antibacterial drugs are urgently needed to address the global issue of
antibiotic resistance. In this context, peptaibols are promising membrane-active peptides …

In the search for new sources of antimicrobials many researchers have investigated
antimicrobial peptides (AMPs) as templates for the design of innovative therapeutics …

Due to their broad-spectrum activity against Gram-negative and Gram-positive bacteria,
natural antimicrobial peptides (AMPs) and their synthetic analogs have emerged as …

Peptaibiotics are a group of membrane active peptides of fungal origin. They typically
contain α-aminoisobutyric acid (Aib; 1-letter code, U) and other non-coded residues (Toniolo …

Peptaibols are peculiar peptides produced by fungi as weapons against other
microorganisms. Previous studies showed that peptaibols are promising peptide-based …

Trichogin GA IV, isolated from the fungus Trichoderma longibrachiatum, is the prototype of
lipopeptaibols, the sub-class of short-length peptaibiotics exhibiting membrane-modifying …

Introduction Antimicrobial peptides are proving to be promising lead compounds for
therapeutics. The major disadvantage of antimicrobial peptides is their proteolytic instability …

Bacterial resistance to conventional antibiotics is a global threat that has spurred the
development of antimicrobial peptides (AMPs) and their mimetics as novel anti-infective …

Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …

The field of drug discovery and development has seen tremendous activity over the past
decade to better tackle the increasing occurrence of drug‐resistant bacterial infections and …