Targeting regulated cell death with plant natural compounds for cancer therapy: A revisited review of apoptosis, autophagy‐dependent cell death, and necroptosis

Y Yang, Y Chen, JH Wu, Y Ren, B Liu… - Phytotherapy …, 2023 - Wiley Online Library
Regulated cell death (RCD) refers to programmed cell death regulated by various protein
molecules, such as apoptosis, autophagy‐dependent cell death, and necroptosis …

Targeting regulated cell death (RCD) with small-molecule compounds in cancer therapy: A revisited review of apoptosis, autophagy-dependent cell death and …

W Liu, W Jin, S Zhu, Y Chen, B Liu - Drug Discovery Today, 2022 - Elsevier
Evasion of regulated cell death (RCD), mainly referring to apoptosis, autophagy-dependent
cell death, necroptosis, and other subroutines, is one of the well-established hallmarks of …

Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis

H Gali-Muhtasib, R Hmadi, M Kareh, R Tohme… - Apoptosis, 2015 - Springer
Despite remarkable progress in the discovery and development of novel cancer
therapeutics, cancer remains the second leading cause of death in the world. For many …

[HTML][HTML] The most competent plant-derived natural products for targeting apoptosis in cancer therapy

S Rajabi, M Maresca, AV Yumashev, R Choopani… - Biomolecules, 2021 - mdpi.com
Cancer is a challenging problem for the global health community, and its increasing burden
necessitates seeking novel and alternative therapies. Most cancers share six basic …

Natural compounds modulate the crosstalk between apoptosis-and autophagy-regulated signaling pathways: Controlling the uncontrolled expansion of tumor cells

C Braicu, O Zanoaga, AA Zimta, AB Tigu… - Seminars in Cancer …, 2022 - Elsevier
Due to the high number of annual cancer–related deaths, and the economic burden that this
malignancy affects today's society, the study of compounds isolated from natural sources …

The application of natural products in cancer therapy by targeting apoptosis pathways

Y Wang, J Zhong, J Bai, R Tong, F An… - Current Drug …, 2018 - ingentaconnect.com
Background: Apoptosis is one of the pathways of programmed cell death (PCD), which leads
to pathognomic cellular changes different from cellular necrosis. It includes the death …

From nature to bedside: Pro-survival and cell death mechanisms as therapeutic targets in cancer treatment

C Cerella, MH Teiten, F Radogna, M Dicato… - Biotechnology …, 2014 - Elsevier
Cell death is an important physiological regulator during development, tissue homeostasis
and stress response but it is also a protective tumor suppressive mechanism. Tumor cells …

Natural compounds as modulators of non-apoptotic cell death in cancer cells

L Miguel Guaman-Ortiz… - Current …, 2017 - ingentaconnect.com
Cell death is an innate capability of cells to be removed from microenvironment, if and when
they are damaged by multiple stresses. Cell death is often regulated by multiple molecular …

[HTML][HTML] Modulation of apoptosis by natural products for cancer therapy

S Fulda - Planta medica, 2010 - thieme-connect.com
Natural products can exhibit many beneficial effects on human health. As far as cancer is
concerned, naturally occurring compounds have been reported to prevent tumorigenesis …

[HTML][HTML] Phytochemicals as a complement to cancer chemotherapy: pharmacological modulation of the autophagy-apoptosis pathway

MA Rahman, MA Hannan, R Dash… - Frontiers in …, 2021 - frontiersin.org
Bioactive plant derived compounds are important for a wide range of therapeutic
applications, and some display promising anticancer properties. Further evidence suggests …