Objective To assess the impact of osteoarthritis (OA) on the meniscus by comparing
transcripts and biological processes in the meniscus between patients with and without OA …

Objective Meniscus tears are associated with a heightened risk of osteoarthritis. This study
aimed to advance our understanding of the metabolic state of injured human meniscus at …

Objective To compare the transcriptome of articular cartilage from knees with meniscus tears
to knees with end-stage osteoarthritis (OA). Design Articular cartilage was collected from the …

ABSTRACT Purpose/Aim: Meniscus tears are a common injury to the knee associated with
the development of osteoarthritis. Gene expression in the injured meniscus may be …

Objective Traumatic and degenerative meniscal tears have different anatomic features and
different proposed etiologies, yet both are associated with the development or progression …

Objective Higher body mass index (BMI) increases the risk of meniscus injury and knee
osteoarthritis (OA). However, it is unknown if and how obesity affects meniscus biology. We …

Background Menisci play a vital role in load transmission, shock absorption and joint
stability. There is increasing evidence suggesting that OA menisci may not merely be …

Meniscus plays an important role in joint homeostasis. Tear or degeneration of meniscus
might facilitate the process of knee osteoarthritis (OA). Hence, to investigate the …

Injury to any individual structure in the knee interrupts the overall function of the joint and
initiates a cascade of biological and biomechanical changes whose endpoint is often …

Objectives The heterogeneity of meniscus cells and the mechanism of meniscus
degeneration is not well understood. Here, single-cell RNA sequencing (scRNA-seq) was …