The test's popularity has led to a hugely expensive public health disaster. It's an issue I am
painfully familiar with—I discovered PSA in 1970. As Congress searches for ways to cut …

Every year, more than a million men undergo painful needle biopsies for prostate cancer,
and upward of 100,000 have radical prostatectomies, resulting in incontinence and …

Prostate cancer is the second leading cause of cancer death among men. Because it has
been thought that identifying the disease earlier leads to better outcomes, there has been a …

The death rate from prostate cancer in the US has been declining for several years, but the
disease still claims too many lives. It will strike an estimated 184,500 men this year and …

In the United States, most men over the age of 50 years have had a prostate-specific antigen
(PSA) test, 1 despite the absence of evidence from large, randomized trials of a net benefit …

The Commentary in the December issue of Cancer'on standardization of PSA
immunoassays is misleading and potentially harmful in our efforts at Stanford to achieve …

Prostate specific antigen has profoundly affected the detection of prostate cancer in the
United States. First identified in 1970, it was initially used to measure the response to …

Screening, for any disease, is often mired in controversy. If there should be any doubts
regarding this observation, one only needs to examine the recent uproar surrounding …

Background: The finding that some men with a normal prostate-specific antigen (PSA) level
(ie, less than 4 ng/mL) nonetheless have microscopic evidence of prostate cancer has led to …

In response to a marked increase in the use of an available test, Group Health Cooperative
of Puget Sound (GHC) evaluated the use of prostatic specific antigen (PSA) as a screening …