[HTML][HTML] SARS-CoV-2 niches in human placenta revealed by spatial transcriptomics
ER Barrozo, MD Seferovic, ECC Castro, AM Major… - Med, 2023 - cell.com
Background Functional placental niches are presumed to spatially separate maternal-fetal
antigens and restrict the vertical transmission of pathogens. We hypothesized a high …
antigens and restrict the vertical transmission of pathogens. We hypothesized a high …
Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures
N Stylianou, I Sebina, N Matigian… - Clinical & …, 2024 - Wiley Online Library
Abstract Objectives Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2)
virus infection in pregnancy is associated with higher incidence of placental dysfunction …
virus infection in pregnancy is associated with higher incidence of placental dysfunction …
Consistent localization of SARS-CoV-2 spike glycoprotein and ACE2 over TMPRSS2 predominance in placental villi of 15 COVID-19 positive maternal-fetal dyads
E Taglauer, Y Benarroch, K Rop, E Barnett… - Placenta, 2020 - Elsevier
Introduction While the COVID-19 pandemic continues to have a significant global health
impact, rates of maternal to infant vertical transmission remain low (< 5%). Parenchymal …
impact, rates of maternal to infant vertical transmission remain low (< 5%). Parenchymal …
Cellular and molecular atlas of the placenta from a COVID‐19 pregnant woman infected at midgestation highlights the defective impacts on foetal health
J Chen, L Du, F Wang, X Shao, X Wang, W Yu… - Cell …, 2022 - Wiley Online Library
Objectives The impacts of the current COVID‐19 pandemic on maternal and foetal health
are enormous and of serious concern. However, the influence of SARS‐CoV‐2 infection at …
are enormous and of serious concern. However, the influence of SARS‐CoV‐2 infection at …
[HTML][HTML] SARS-CoV-2 footprints in the placenta: what we know after three years of the pandemic
V Tosto, A Meyyazhagan, M Alqasem… - Journal of Personalized …, 2023 - mdpi.com
As the COVID-19 pandemic continues into its third year, there is accumulating evidence on
the consequences of maternal infection. Emerging data indicate increased obstetrics risks …
the consequences of maternal infection. Emerging data indicate increased obstetrics risks …
[HTML][HTML] SARS-CoV-2 infects syncytiotrophoblast and activates inflammatory responses in the placenta
SARS-CoV-2 infection during pregnancy leads to an increased risk of adverse pregnancy
outcomes. Although the placenta itself can be a target of virus infection, most neonates are …
outcomes. Although the placenta itself can be a target of virus infection, most neonates are …
[HTML][HTML] Severe SARS-CoV-2 placenta infection can impact neonatal outcome in the absence of vertical transmission
FM Cribiù, R Erra, L Pugni… - The Journal of …, 2021 - Am Soc Clin Investig
The effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on
the pathophysiology of the placenta and its impact on pregnancy outcome has not yet been …
the pathophysiology of the placenta and its impact on pregnancy outcome has not yet been …
[HTML][HTML] SARS-CoV2 vertical transmission with adverse effects on the newborn revealed through integrated immunohistochemical, electron microscopy and molecular …
F Facchetti, M Bugatti, E Drera, C Tripodo, E Sartori… - …, 2020 - thelancet.com
Background. The occurrence of trans-placental transmission of severe acute respiratory
syndrome corona virus 2 (SARS-CoV-2) infection remains highly debated. Placental …
syndrome corona virus 2 (SARS-CoV-2) infection remains highly debated. Placental …
[HTML][HTML] Single-cell RNA-seq identifies cell subsets in human placenta that highly expresses factors driving pathogenesis of SARS-CoV-2
N Ashary, A Bhide, P Chakraborty, S Colaco… - Frontiers in cell and …, 2020 - frontiersin.org
Infection by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) results in
the novel coronavirus disease COVID-19, which has posed a serious threat globally …
the novel coronavirus disease COVID-19, which has posed a serious threat globally …
[HTML][HTML] Maternal respiratory SARS-CoV-2 infection in pregnancy is associated with a robust inflammatory response at the maternal-fetal interface
Background Pregnant women are at increased risk for severe outcomes from coronavirus
disease 2019 (COVID-19), but the pathophysiology underlying this increased morbidity and …
disease 2019 (COVID-19), but the pathophysiology underlying this increased morbidity and …
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