OXA β-lactamases

BA Evans, SGB Amyes - Clinical microbiology reviews, 2014 - Am Soc Microbiol
The OXA β-lactamases were among the earliest β-lactamases detected; however, these
molecular class D β-lactamases were originally relatively rare and always plasmid …

Cloning and nucleotide sequence analysis of a gene encoding an OXA-derived beta-lactamase in Acinetobacter baumannii

J Vila, M Navia, J Ruiz, C Casals - Antimicrobial agents and …, 1997 - Am Soc Microbiol
A clinical strain of Acinetobacter baumannii (strain Ab41) that was resistant to all beta-lactam
antibiotics tested except ceftazidime, ceftriaxone, ceftizoxime, and imipenem produced three …

[HTML][HTML] OXA-51-like β-lactamases and their association with particular epidemic lineages of Acinetobacter baumannii

BA Evans, A Hamouda, KJ Towner… - Clinical microbiology and …, 2008 - Elsevier
Sixty diverse clinical Acinetobacter baumannii isolates of worldwide origin were assigned to
sequence groups, based on a multiplex PCR for the ompA, csuE and bla OXA-51-like …

OXA beta-lactamase-mediated carbapenem resistance in Acinetobacter baumannii

SM Amudhan, U Sekar, K Arunagiri, B Sekar - Indian Journal of Medical …, 2011 - Elsevier
Objectives: Acinetobacter baumannii is a significant pathogen in health care settings. In
recent years, an increase in carbapenem resistance among A. baumannii due to Ambler …

Characterization of OXA-25, OXA-26, and OXA-27, molecular class D β-lactamases associated with carbapenem resistance in clinical isolates of Acinetobacter …

M Afzal-Shah, N Woodford… - Antimicrobial agents and …, 2001 - Am Soc Microbiol
Carbapenem resistance in Acinetobacter spp. is increasingly being associated with OXA-
type β-lactamases with weak hydrolytic activity against imipenem and meropenem. Such …

OXA β-lactamases in Acinetobacter: the story so far

S Brown, S Amyes - Journal of Antimicrobial Chemotherapy, 2006 - academic.oup.com
The emergence of carbapenem resistance in Acinetobacter baumannii has become a global
concern since these β-lactams are often the only effective treatment left against many …

OXA-58, a Novel Class D β-Lactamase Involved in Resistance to Carbapenems in Acinetobacter baumannii

L Poirel, S Marqué, C Héritier, C Segonds… - Antimicrobial agents …, 2005 - Am Soc Microbiol
ABSTRACT A carbapenem-resistant Acinetobacter baumannii strain was isolated in
Toulouse, France, in 2003. Cloning and expression in Escherichia coli identified the …

OXA-235, a novel class D β-lactamase involved in resistance to carbapenems in Acinetobacter baumannii

PG Higgins, FJ Pérez-Llarena, E Zander… - Antimicrobial agents …, 2013 - Am Soc Microbiol
We investigated the mechanism of carbapenem resistance in 10 Acinetobacter baumannii
strains isolated from the United States and Mexico between 2005 and 2009. The detection of …

OXA-24, a Novel Class D β-Lactamase with Carbapenemase Activity in an Acinetobacter baumanniiClinical Strain

G Bou, A Oliver, J Martínez-Beltrán - Antimicrobial agents and …, 2000 - Am Soc Microbiol
ABSTRACT Acinetobacter baumannii RYC 52763/97, a clinical isolate involved in a
prolonged nosocomial outbreak at our hospital, was resistant to all β-lactams tested …

Overexpression of the Naturally Occurring blaOXA-51 Gene in Acinetobacter baumannii Mediated by Novel Insertion Sequence ISAba9

S Figueiredo, L Poirel, A Papa… - Antimicrobial agents …, 2009 - Am Soc Microbiol
Resistance to carbapenems in Acinetobacter baumannii is increasingly reported and is
mostly associated with expression of carbapenemases (3, 6). Those carbapenemases are …