Tendon-bioinspired wavy nanofibrous scaffolds provide tunable anisotropy and promote tenogenesis for tendon tissue engineering

S Wu, J Liu, Y Qi, J Cai, J Zhao, B Duan… - Materials Science and …, 2021 - Elsevier
The development of tendon-biomimetic nanofibrous scaffolds with mesenchymal stem cells
may represent a promising strategy to improve the unsatisfactory outcomes of traditional …

Electrospun aligned poly (ε-caprolactone) nanofiber yarns guiding 3D organization of tendon stem/progenitor cells in tenogenic differentiation and tendon repair

Q Yang, J Li, W Su, L Yu, T Li, Y Wang… - … in Bioengineering and …, 2022 - frontiersin.org
Hierarchical anisotropy structure directing 3D cellular orientation plays a crucial role in
designing tendon tissue engineering scaffolds. Despite recent development of fabrication …

Enhancing the biomechanical performance of anisotropic nanofibrous scaffolds in tendon tissue engineering: reinforcement with cellulose nanocrystals

RMA Domingues, S Chiera… - Advanced …, 2016 - Wiley Online Library
Anisotropically aligned electrospun nanofibrous scaffolds based on natural/synthetic
polymer blends have been established as a reasonable compromise between biological …

Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation

S Wu, Y Wang, PN Streubel, B Duan - Acta biomaterialia, 2017 - Elsevier
Non-woven nanofibrous scaffolds have been developed for tendon graft application by
using electrospinning strategies. However, electrospun nanofibrous scaffolds face some …

A novel electrospun-aligned nanoyarn-reinforced nanofibrous scaffold for tendon tissue engineering

C Yang, G Deng, W Chen, X Ye, X Mo - Colloids and Surfaces B …, 2014 - Elsevier
An electrospun-aligned nanoyarn-reinforced nanofibrous scaffold (NRS) was developed for
tendon tissue engineering to improve mechanical strength and cell infiltration. The novel …

Tenogenic adipose-derived stem cell sheets with nanoyarn scaffolds for tendon regeneration

S Chen, J Wang, Y Chen, X Mo, C Fan - Materials Science and …, 2021 - Elsevier
Tissue engineering, especially cell sheets-based engineering, offers a promising approach
to tendon regeneration; however, obtaining a sufficient source of cells for tissue engineering …

Development of high resilience spiral wound suture-embedded gelatin/PCL/heparin nanofiber membrane scaffolds for tendon tissue engineering

TG Darshan, CH Chen, CY Kuo, KT Shalumon… - International Journal of …, 2022 - Elsevier
This study develops a spiral wound scaffold based on gelatin/PCL/heparin (GPH) nanofiber
membranes for tendon tissue engineering. By embedding sutures in dual layers of aligned …

Aligned nanofiber topography directs the tenogenic differentiation of mesenchymal stem cells

TL Popielarczyk, AS Nain, JG Barrett - Applied Sciences, 2017 - mdpi.com
Tendon is commonly injured, heals slowly and poorly, and often suffers re-injury after
healing. This is due to failure of tenocytes to effectively remodel tendon after injury to …

Platelet-Derived extracellular vesicles promote tenogenic differentiation of stem cells on bioengineered living fibers

AL Graça, RMA Domingues, M Gomez-Florit… - International journal of …, 2023 - mdpi.com
Tendon mimetic scaffolds that recreate the tendon hierarchical structure and niche have
increasing potential to fully restore tendon functionality. However, most scaffolds lack …

Constructing high-strength nano-micro fibrous woven scaffolds with native-like anisotropic structure and immunoregulatory function for tendon repair and regeneration

J Cai, J Liu, J Xu, Y Li, T Zheng, T Zhang, K Han… - …, 2023 - iopscience.iop.org
Tendon injuries are common debilitating musculoskeletal diseases with high treatment
expenditure in sports medicine. The development of tendon-biomimetic scaffolds may be …