Cerebral ischemia is accompanied by a marked inflammatory reaction that is initiated by
ischemia-induced expression of cytokines, adhesion molecules, and other inflammatory …

In experimental models of stroke, inflammation appears to contribute to cerebral ischemic
injury. Clinical trials that are aimed at limiting the postischemic inflammatory response …

Brain infarction causes tissue death by ischemia due to occlusion of the cerebral vessels
and recent work has shown that post stroke inflammation contributes significantly to the …

Inflammation is a defense reaction against diverse insults that serves to remove noxious
agents and to limit their detrimental effects. There is increasing evidence that post-ischemic …

Numerous studies have indicated that inflammation plays a key role in ischaemic brain
injury. Brain ischaemia–reperfusion‐induced inflammatory responses include increased …

Acute systemic inflammatory reaction superimposed on chronic low-grade inflammation
accompanies acute ischemic stroke. Elevated blood levels of systemic inflammatory markers …

Ischemic stroke is characterized by the disruption of cerebral blood flow (CBF). This
reduction of CBF results in energy failure and secondary biochemical disturbances, eliciting …

Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …

Ischemic stroke is a leading cause of death and disability in developed countries. Yet, in
spite of substantial research and development efforts, no specific therapy for stroke is …

A growing body of evidence, primarily from animal models of cerebral ischemia and
preliminary human studies, indicates that inflammatory mechanisms contribute to secondary …