Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
We present a proteogenomic study of 108 human papilloma virus (HPV)-negative head and
neck squamous cell carcinomas (HNSCCs). Proteomic analysis systematically catalogs …
neck squamous cell carcinomas (HNSCCs). Proteomic analysis systematically catalogs …
[HTML][HTML] The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies
D Martin, MC Abba, AA Molinolo, L Vitale-Cross… - Oncotarget, 2014 - ncbi.nlm.nih.gov
The recent elucidation of the genomic landscape of head and neck squamous cell
carcinoma (HNSCC) has provided a unique opportunity to develop selective cancer …
carcinoma (HNSCC) has provided a unique opportunity to develop selective cancer …
Pharmacogenomic landscape of head and neck squamous cell carcinoma informs precision oncology therapy
Z Gu, Y Yao, G Yang, G Zhu, Z Tian, R Wang… - Science translational …, 2022 - science.org
Head and neck squamous cell carcinoma (HNSCC) is a common and frequently lethal
cancer with few therapeutic options. In particular, there are few effective targeted therapies …
cancer with few therapeutic options. In particular, there are few effective targeted therapies …
Genomic and transcriptomic characterization links cell lines with aggressive head and neck cancers
Cell lines are important tools for biological and preclinical investigation, and establishing
their relationship to genomic alterations in tumors could accelerate functional and …
their relationship to genomic alterations in tumors could accelerate functional and …
[HTML][HTML] Molecular landscape of head and neck cancer and implications for therapy
CS Farah - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinomas (HNSCC) arising from the oral cavity, pharynx,
and larynx constitute the 6 th most common human cancer. Human papillomavirus (HPV) …
and larynx constitute the 6 th most common human cancer. Human papillomavirus (HPV) …
Genomic landscapes of EBV-associated nasopharyngeal carcinoma vs. HPV-associated head and neck cancer
Epstein-Barr virus-positive nasopharyngeal carcinoma (EBV (+) NPC), and human
papillomavirus-positive head and neck squamous cell carcinoma (HPV (+) HNSCC) are two …
papillomavirus-positive head and neck squamous cell carcinoma (HPV (+) HNSCC) are two …
Genomic insights into head and neck cancer
TN Beck, EA Golemis - Cancers of the head & neck, 2016 - Springer
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide and is frequently impervious to curative treatment efforts. Similar to other cancers …
worldwide and is frequently impervious to curative treatment efforts. Similar to other cancers …
Therapeutic insights from genomic studies of head and neck squamous cell carcinomas
PS Hammerman, DN Hayes, JR Grandis - Cancer discovery, 2015 - AACR
Large and comprehensive genomic surveys of head and neck squamous cell carcinomas
(HNSCC) are now greatly increasing our understanding of the diversity of this disease and …
(HNSCC) are now greatly increasing our understanding of the diversity of this disease and …
Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma
Head and neck squamous cell carcinoma (HNSCC) includes a subset of cancers driven by
human papillomavirus (HPV). Here we use single-cell RNA-seq to profile both HPV-positive …
human papillomavirus (HPV). Here we use single-cell RNA-seq to profile both HPV-positive …
Molecular profiling of head and neck squamous cell carcinoma
R Feldman, Z Gatalica, J Knezetic, S Reddy… - Head & …, 2016 - Wiley Online Library
Background Head and neck squamous cell carcinoma (HNSCC) exhibits high rates of
recurrence, and with few approved targeted agents, novel treatments are needed. We …
recurrence, and with few approved targeted agents, novel treatments are needed. We …
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