Central nervous system involvement in adults with acute leukemia: diagnosis, prevention, and management

S Paul, NJ Short - Current oncology reports, 2022 - Springer
Abstract Purpose of Review Recent treatment advances in both acute myeloid leukemia and
acute lymphoblastic leukemia have drastically improved outcomes for these diseases, but …

Central nervous system prophylaxis and treatment in acute leukemias

SY Wu, NJ Short, L Nasr, BS Dabaja… - Current treatment options …, 2022 - Springer
Opinion statement Improvements in systemic therapy in the treatment of acute lymphoblastic
leukemia (ALL) and acute myeloid leukemia (AML) have improved patient outcomes and …

How I prevent and treat central nervous system disease in adults with acute lymphoblastic leukemia

NE Kopmar, RD Cassaday - Blood, 2023 - ashpublications.org
The central nervous system (CNS) is the most important site of extramedullary disease in
adults with acute lymphoblastic leukemia (ALL). Although CNS disease is identified only in a …

[HTML][HTML] Central nervous system involvement in adult acute lymphoblastic leukemia: diagnostic tools, prophylaxis, and therapy

MI Del Principe, L Maurillo, F Buccisano… - … journal of hematology …, 2014 - ncbi.nlm.nih.gov
In adult patients with acute lymphoblastic leukemia (ALL), Central Nervous System (CNS)
involvement is associated with a very poor prognosis. The diagnostic assessment of this …

[HTML][HTML] Identification of risk groups for development of central nervous system leukemia in adults with acute lymphocytic leukemia

HM Kantarjian, RS Walters, TL Smith, MJ Keating… - Blood, 1988 - Elsevier
The risk of development of CNS leukemia was investigated in 153 adults with acute
lymphocytic leukemia (ALL) who received systemic combination chemotherapy without CNS …

Central nervous system prophylaxis in adults with acute lymphoblastic leukemia: current and emerging therapies

E Jabbour, D Thomas, J Cortes, HM Kantarjian… - Cancer, 2010 - Wiley Online Library
Central nervous system (CNS) recurrence continues to be a significant complication in the
treatment of adult patients with acute lymphoblastic leukemia (ALL). Preventing CNS …

Managing CNS disease in adults with acute lymphoblastic leukemia

RA Larson - Leukemia & Lymphoma, 2018 - Taylor & Francis
The central nervous system (CNS) is an important site of involvement by acute lymphoblastic
leukemia (ALL) in adults. The prevalence is sufficiently high that prophylactic treatment is …

[HTML][HTML] A narrative review of central nervous system involvement in acute leukemias

D Deak, N Gorcea-Andronic, V Sas… - Annals of …, 2021 - ncbi.nlm.nih.gov
Acute leukemias (both myeloid and lymphoblastic) are a group of diseases for which each
year more successful therapies are implemented. However, in a subset of cases the overall …

Central nervous system involvement in adult acute lymphocytic leukemia

J Cortes - Hematology/oncology clinics of North America, 2001 - Elsevier
Central nervous system (CNS) involvement is identified at the time of diagnosis in less than
5% of children with acute lymphocytic leukemia (ALL). 9 Before the institution of adequate …

The incidence of central nervous system leukemia in adults with acute leukemia

RW Wolk, SR Masse, R Conklin, EJ Freireich - Cancer, 1974 - Wiley Online Library
To determine the incidence of central nervous system leukemia (CNSL) in adults with acute
leukemia (AL) we studied 299 patients admitted from 1966 to 1971, and reviewed 170 …