[PDF][PDF] Molecular docking and simulation studies of medicinal plant phytochemicals with Leishmania donovani adenosylmethionine decarboxylase
Visceral leishmaniasis is a neglected endemic disease caused by the intramacrophage
obligate parasite, Leishmania donovani that affects millions of people worldwide. Visceral …
obligate parasite, Leishmania donovani that affects millions of people worldwide. Visceral …
Mechanistic insights into the dual inhibition strategy for checking Leishmaniasis
Leishmaniasis is an endemic disease mainly caused by the protozoan Leishmania
donovani (Ld). Polyamines have been identified as essential organic compounds for the …
donovani (Ld). Polyamines have been identified as essential organic compounds for the …
Studies on ornithine decarboxylase of Leishmania donovani: structure modeling and inhibitor docking
D Chakraborty, P Saravanan, S Patra… - Medicinal Chemistry …, 2013 - Springer
Leishmaniasis is a detrimental disease caused by the parasite Leishmania which has a
unique redox metabolism involving trypanothione. Trypanothione delivers reducing …
unique redox metabolism involving trypanothione. Trypanothione delivers reducing …
[PDF][PDF] Molecular docking approach to locate the potent anti-leishmanial agent
Leishmaniasis represents endemic infections that occur predominantly in tropical and
subtropical regions, caused by Leishmania protozoan parasites and transmitted via the bite …
subtropical regions, caused by Leishmania protozoan parasites and transmitted via the bite …
Drug repositioning to discover novel ornithine decarboxylase inhibitors against visceral leishmaniasis
Visceral leishmaniasis (VL) is caused by Leishmania donovani (Ld), and most cases occur
in Brazil, East Africa, and India. The treatment for VL is limited and has many adverse effects …
in Brazil, East Africa, and India. The treatment for VL is limited and has many adverse effects …
Molecular modeling and virtual screening approach to discover potential antileishmanial inhibitors against ornithine decarboxylase
R Kumar Pandey, P Prajapati, S Goyal… - … chemistry & high …, 2016 - ingentaconnect.com
Background: Visceral leishmaniasis (VL) is a tropical neglected disease, which encounters
poorest of poor people living in Asia, Africa and Latin America; causing the mortality of more …
poorest of poor people living in Asia, Africa and Latin America; causing the mortality of more …
Screening and identification of potential inhibitor for visceral leishmaniasis (VL) through computational analysis
N Shaslinah, P Sangavi, R Sangeetha… - Journal of Genetic …, 2022 - Elsevier
Aim The aim of this investigation is to detect potential inhibitor for visceral leishmaniasis
through computational analysis. Background Leishmaniasis is categorized as a vector born …
through computational analysis. Background Leishmaniasis is categorized as a vector born …
Computational multi‐target approach to target essential enzymes of Leishmania donovani using comparative molecular dynamic simulations and MMPBSA analysis
D Saha, A Nath Jha - Phytochemical Analysis, 2023 - Wiley Online Library
Introduction Visceral leishmaniasis (VL) is caused by Leishmania donovani. The purine and
pyrimidine pathways are essential for L. donovani. Simultaneously inhibiting multiple targets …
pyrimidine pathways are essential for L. donovani. Simultaneously inhibiting multiple targets …
Identification of two natural compound inhibitors of Leishmania donovani Spermidine Synthase (SpdS) through molecular docking and dynamic studies
V VM, VK Dubey, K Ponnuraj - Journal of Biomolecular Structure …, 2018 - Taylor & Francis
Visceral leishmaniasis caused by the protozoan Leishmania donovan i is the most severe
form of leishmaniasis and it is potentially lethal if untreated. Despite the availability of drugs …
form of leishmaniasis and it is potentially lethal if untreated. Despite the availability of drugs …
Identification of potential inhibitors of Leishmania donovani Sterol 24-C- methyltransferase: in silico and in vitro studies
S Saha, R Srivastava, P Sarma, TK Bhatt… - Molecular …, 2023 - Taylor & Francis
Leishmania donovani causes the neglected tropical disease visceral leishmaniasis. There is
currently no vaccine available to combat the disease. Therefore, chemotherapy is the only …
currently no vaccine available to combat the disease. Therefore, chemotherapy is the only …