ZNF677 suppresses Akt phosphorylation and tumorigenesis in thyroid cancer
Y Li, Q Yang, H Guan, B Shi, M Ji, P Hou - Cancer research, 2018 - AACR
The zinc finger protein 677 (ZNF677) belongs to the zinc finger protein family, which
possesses transcription factor activity by binding sequence-specific DNA. Previous studies …
possesses transcription factor activity by binding sequence-specific DNA. Previous studies …
[HTML][HTML] Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell …
J Zhang, X Wen, N Liu, YQ Li, XR Tang… - Journal of Experimental …, 2017 - Springer
Background Epigenetic abnormalities play important roles in nasopharyngeal cancer (NPC),
however, the epigenetic changes associated with abnormal cell proliferation remain unclear …
however, the epigenetic changes associated with abnormal cell proliferation remain unclear …
ZNF143-mediated H3K9 trimethylation upregulates CDC6 by activating MDIG in hepatocellular carcinoma
L Zhang, Q Huo, C Ge, F Zhao, Q Zhou, X Chen, H Tian… - Cancer Research, 2020 - AACR
Abstract Zinc finger protein 143 (ZNF143) belongs to the zinc finger protein family and
possesses transcription factor activity by binding sequence-specific DNA. The exact …
possesses transcription factor activity by binding sequence-specific DNA. The exact …
A novel 19q13 nucleolar zinc finger protein suppresses tumor cell growth through inhibiting ribosome biogenesis and inducing apoptosis but is frequently silenced in …
Y Cheng, P Liang, H Geng, Z Wang, L Li… - Molecular cancer …, 2012 - AACR
Epigenetic disruption of tumor suppressor genes is frequently involved in tumorigenesis. We
identified a novel 19q13 KRAB domain-containing zinc finger protein, ZNF545/ZFP82 …
identified a novel 19q13 KRAB domain-containing zinc finger protein, ZNF545/ZFP82 …
[HTML][HTML] DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers
G Heller, C Altenberger, B Schmid, M Marhold… - Oncotarget, 2015 - ncbi.nlm.nih.gov
In our study, we investigated the role of ZNF677 in non-small cell lung cancers (NSCLC). By
comparing ZNF677 expression in primary tumor (TU) and in the majority of cases also of …
comparing ZNF677 expression in primary tumor (TU) and in the majority of cases also of …
[HTML][HTML] The zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-κB signaling
W Wang, M Guo, L Hu, J Cai, Y Zeng, J Luo… - Journal of Biological …, 2012 - ASBMB
Cervical cancer is one of the most common tumors affecting women's health worldwide.
Although human papillomavirus can be detected in nearly all cases, the mechanism of …
Although human papillomavirus can be detected in nearly all cases, the mechanism of …
[HTML][HTML] Epigenetic-Mediated Downregulation of Zinc Finger Protein 671 (ZNF671) Predicts Poor Prognosis in Multiple Solid Tumors
J Zhang, Z Zheng, J Zheng, T Xie, Y Tian, R Li… - Frontiers in …, 2019 - frontiersin.org
Zinc finger protein 671 (ZNF671) is a member of the largest transcription factor family in the
human genome. However, the methylation status, expression, and prognostic role of …
human genome. However, the methylation status, expression, and prognostic role of …
[HTML][HTML] Zinc-finger protein 545 inhibits cell proliferation as a tumor suppressor through inducing apoptosis and is disrupted by promoter methylation in breast cancer
Krüppel-associated box-containing zinc finger proteins (KRAP-ZFPs) are well recognized as
key regulators of transcription, which play a crucial role in the regulation of cell proliferation …
key regulators of transcription, which play a crucial role in the regulation of cell proliferation …
[HTML][HTML] Zinc finger proteins in cancer progression
Zinc finger proteins are the largest transcription factor family in human genome. The diverse
combinations and functions of zinc finger motifs make zinc finger proteins versatile in …
combinations and functions of zinc finger motifs make zinc finger proteins versatile in …
KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas
Zinc finger transcription factors are involved broadly in development and tumorigenesis.
Here, we report that the little studied zinc finger transcription factor ZNF382 functions as a …
Here, we report that the little studied zinc finger transcription factor ZNF382 functions as a …