ZNF677 suppresses Akt phosphorylation and tumorigenesis in thyroid cancer

Y Li, Q Yang, H Guan, B Shi, M Ji, P Hou - Cancer research, 2018 - AACR
The zinc finger protein 677 (ZNF677) belongs to the zinc finger protein family, which
possesses transcription factor activity by binding sequence-specific DNA. Previous studies …

[HTML][HTML] Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell …

J Zhang, X Wen, N Liu, YQ Li, XR Tang… - Journal of Experimental …, 2017 - Springer
Background Epigenetic abnormalities play important roles in nasopharyngeal cancer (NPC),
however, the epigenetic changes associated with abnormal cell proliferation remain unclear …

ZNF143-mediated H3K9 trimethylation upregulates CDC6 by activating MDIG in hepatocellular carcinoma

L Zhang, Q Huo, C Ge, F Zhao, Q Zhou, X Chen, H Tian… - Cancer Research, 2020 - AACR
Abstract Zinc finger protein 143 (ZNF143) belongs to the zinc finger protein family and
possesses transcription factor activity by binding sequence-specific DNA. The exact …

A novel 19q13 nucleolar zinc finger protein suppresses tumor cell growth through inhibiting ribosome biogenesis and inducing apoptosis but is frequently silenced in …

Y Cheng, P Liang, H Geng, Z Wang, L Li… - Molecular cancer …, 2012 - AACR
Epigenetic disruption of tumor suppressor genes is frequently involved in tumorigenesis. We
identified a novel 19q13 KRAB domain-containing zinc finger protein, ZNF545/ZFP82 …

[HTML][HTML] DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers

G Heller, C Altenberger, B Schmid, M Marhold… - Oncotarget, 2015 - ncbi.nlm.nih.gov
In our study, we investigated the role of ZNF677 in non-small cell lung cancers (NSCLC). By
comparing ZNF677 expression in primary tumor (TU) and in the majority of cases also of …

[HTML][HTML] The zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-κB signaling

W Wang, M Guo, L Hu, J Cai, Y Zeng, J Luo… - Journal of Biological …, 2012 - ASBMB
Cervical cancer is one of the most common tumors affecting women's health worldwide.
Although human papillomavirus can be detected in nearly all cases, the mechanism of …

[HTML][HTML] Epigenetic-Mediated Downregulation of Zinc Finger Protein 671 (ZNF671) Predicts Poor Prognosis in Multiple Solid Tumors

J Zhang, Z Zheng, J Zheng, T Xie, Y Tian, R Li… - Frontiers in …, 2019 - frontiersin.org
Zinc finger protein 671 (ZNF671) is a member of the largest transcription factor family in the
human genome. However, the methylation status, expression, and prognostic role of …

[HTML][HTML] Zinc-finger protein 545 inhibits cell proliferation as a tumor suppressor through inducing apoptosis and is disrupted by promoter methylation in breast cancer

Y Xiao, T Xiang, X Luo, C Li, Q Li, W Peng, L Li, S Li… - PloS one, 2014 - journals.plos.org
Krüppel-associated box-containing zinc finger proteins (KRAP-ZFPs) are well recognized as
key regulators of transcription, which play a crucial role in the regulation of cell proliferation …

[HTML][HTML] Zinc finger proteins in cancer progression

J Jen, YC Wang - Journal of biomedical science, 2016 - Springer
Zinc finger proteins are the largest transcription factor family in human genome. The diverse
combinations and functions of zinc finger motifs make zinc finger proteins versatile in …

KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas

Y Cheng, H Geng, SH Cheng, P Liang, Y Bai, J Li… - Cancer research, 2010 - AACR
Zinc finger transcription factors are involved broadly in development and tumorigenesis.
Here, we report that the little studied zinc finger transcription factor ZNF382 functions as a …