Based on the evidence of a significant communication and connection pathway between the
bone and immune systems, a new science has emerged: osteoimmunology. Indeed, the …

Oxidative stress arises when the level of oxidants exceeds that of antioxidants. It occurs
either when oxidant production is excessive or when antioxidant release is insufficient. This …

Bone is a metabolically active tissue that undergoes continuous remodeling by two
sequential events, bone formation and resorption. These events are strongly linked and …

Objectives The present manuscript aims a detailed characterization of the bone cells
dynamics during physiological bone remodelling and, subsequently, to address the cellular …

Osteoradionecrosis of the jaws (ORNJ) is a severe complication that occurs after
radiotherapy of head and neck malignancies. Clinically, conservative treatments and …

Bone has the unique capacity to heal bony injuries without fibrous scar formation via its
regeneration process and therefore maintains physiological and mechanical characteristics …

Bone is an active tissue, being constantly renewed in healthy individuals with participation of
the immune system to a large extent. Any imbalance between the processes of bone …

Bone infection and inflammation leads to the infiltration of immune cells at the site of
infection, where they modulate the differentiation and function of osteoclasts and osteoblasts …

Maxillofacial bone defects are common medical problems caused by congenital defects,
necrosis, trauma, tumor, inflammation, and fractures non-union. Maxillofacial bone defects …

Aim Osteoimmunology covers the cellular and molecular mechanisms responsible for
inflammatory osteolysis that culminates in the degradation of alveolar bone …