[HTML][HTML] A novel derivative of the fungal antimicrobial peptide plectasin is active against Mycobacterium tuberculosis

E Tenland, N Krishnan, A Rönnholm, S Kalsum… - Tuberculosis, 2018 - Elsevier
Tuberculosis has been reaffirmed as the infectious disease causing most deaths in the
world. Co-infection with HIV and the increase in multi-drug resistant Mycobacterium …

A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy

KU Rao, DI Henderson, N Krishnan, M Puthia… - Scientific Reports, 2021 - nature.com
Alternative ways to prevent and treat infectious diseases are needed. Previously, we
identified a fungal peptide, NZX, that was comparable to rifampicin in lowering M …

Research advances on plectasin and its derivatives as new potential antimicrobial candidates

Z Li, X Wang, X Wang, D Teng, R Mao, Y Hao… - Process …, 2017 - Elsevier
Plectasin is a cationic antimicrobial peptide (AMP) that is 40 residues long and belongs to
the cysteine-stabilized α-helix and β-sheet superfamily. This peptide, which was first isolated …

Natural antimicrobial peptides against Mycobacterium tuberculosis

M Abedinzadeh, M Gaeini… - Journal of Antimicrobial …, 2015 - academic.oup.com
TB, caused by Mycobacterium tuberculosis, is one the leading infectious diseases
worldwide. There is an urgent need to discover new drugs with unique structures and …

A new high-yielding antimicrobial peptide NZX and its antibacterial activity against Staphylococcus hyicus in vitro/vivo

H Liu, N Yang, R Mao, D Teng, Y Hao, X Wang… - Applied microbiology …, 2020 - Springer
Staphylococcus hyicus, considered as a leading pathogen of exudative epidermitis, is a
serious threat to humans and animals. The emergency of bacterial resistance to antibiotics …

Role of antimicrobial peptides in host defense against mycobacterial infections

P Méndez-Samperio - Peptides, 2008 - Elsevier
Worldwide, tuberculosis remains the most important infectious disease causing morbidity
and death. Currently, at least one-third of the world's population is infected with …

High-Level Expression of the Antimicrobial Peptide Plectasin in Escherichia coli

XL Jing, XG Luo, WJ Tian, LH Lv, Y Jiang, N Wang… - Current …, 2010 - Springer
Plectasin is a defensin-like antimicrobial peptide isolated from a fungus, the saprophytic
ascomycete Pseudoplectania nigrella. Plectasin showed marked antibacterial activity in vitro …

Efficacy of antimicrobial peptoids against Mycobacterium tuberculosis

R Kapoor, PR Eimerman, JW Hardy… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Tuberculosis is a leading cause of death worldwide. Resistance of Mycobacterium to
antibiotics can make treatments less effective in some cases. We tested selected …

Antimicrobial peptides for the treatment of pulmonary tuberculosis, allies or foes?

B Rivas-Santiago… - Current Pharmaceutical …, 2018 - ingentaconnect.com
Tuberculosis is an ancient disease that has become a serious public health issue in recent
years, although increasing incidence has been controlled, deaths caused by Mycobacterium …

Effective Antimicrobial Activity of Plectasin-Derived Antimicrobial Peptides against Staphylococcus aureus Infection in Mammary Glands

L Li, L Wang, Y Gao, J Wang, X Zhao - Frontiers in microbiology, 2017 - frontiersin.org
Staphylococcus aureus (S. aureus) is the causative agent for a wide variety of illnesses
ranging from minor skin infections to life-threatening diseases. Development of antibiotic …