Applications and challenges of CRISPR-Cas gene-editing to disease treatment in clinics

W Liu, L Li, J Jiang, M Wu, P Lin - Precision clinical medicine, 2021 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems
(Cas) are efficient tools for targeting specific genes for laboratory research, agricultural …

Advances in industrial biotechnology using CRISPR-Cas systems

PD Donohoue, R Barrangou, AP May - Trends in biotechnology, 2018 - cell.com
The term 'clustered regularly interspaced short palindromic repeats'(CRISPR) has recently
become synonymous with the genome-editing revolution. The RNA-guided endonuclease …

[HTML][HTML] Clinical applications of the CRISPR/Cas9 genome-editing system: Delivery options and challenges in precision medicine

M Khoshandam, H Soltaninejad, M Mousazadeh… - Genes & …, 2024 - Elsevier
CRISPR/Cas9 is an effective gene editing tool with broad applications for the prevention or
treatment of numerous diseases. It depends on CRISPR (clustered regularly interspaced …

CRISPR-Cas systems: ushering in the new genome editing era

F Perez Rojo, RKM Nyman, AAT Johnson… - …, 2018 - Taylor & Francis
In recent years there has been great progress with the implementation and utilization of
Clustered Regularly Interspaced Palindromic Repeats (CRISPR) and CRISPR-associated …

Wide horizons of CRISPR-Cas-derived technologies for basic biology, agriculture, and medicine

KA Molla, S Karmakar, MT Islam - CRISPR-Cas methods, 2020 - Springer
The discovery and subsequent repurposing of the CRISPR (clustered regularly interspaced
short palindromic repeats) and Cas proteins (CRISPR-associated proteins) has …

Development of CRISPR-Cas systems for genome editing and beyond

F Zhang - Quarterly Reviews of Biophysics, 2019 - cambridge.org
The development of clustered regularly interspaced short-palindromic repeat (CRISPR)-Cas
systems for genome editing has transformed the way life science research is conducted and …

CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine

FV Jacinto, W Link, BI Ferreira - Journal of cellular and …, 2020 - Wiley Online Library
The recent development of the CRISPR/Cas9 system as an efficient and accessible
programmable genome‐editing tool has revolutionized basic science research …

Development and application of CRISPR/Cas9 technologies in genomic editing

C Zhang, R Quan, J Wang - Human molecular genetics, 2018 - academic.oup.com
Genomic editing to correct disease-causing mutations is a promising approach for the
treatment of human diseases. As a simple and programmable nuclease-based genomic …

CRISPR/Cas9 therapeutics: progress and prospects

T Li, Y Yang, H Qi, W Cui, L Zhang, X Fu, X He… - … and Targeted Therapy, 2023 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …

The potential of CRISPR/Cas9 gene editing as a treatment strategy for inherited diseases

SA Abdelnour, L Xie, AA Hassanin, E Zuo… - Frontiers in cell and …, 2021 - frontiersin.org
Clustered regularly interspaced short palindromic repeats (CRISPR) is a promising
innovative technology for genomic editing that offers scientists the chance to edit DNA …