Therapeutic application of small extracellular vesicles (sEVs): pharmaceutical and pharmacokinetic challenges
Y Takakura, A Matsumoto… - Biological and …, 2020 - jstage.jst.go.jp
Small extracellular vesicles (sEVs), including exosomes as typical example, are cell-derived
vesicles comprising lipid bilayer with a diameter approximately 100 nm. sEVs are …
vesicles comprising lipid bilayer with a diameter approximately 100 nm. sEVs are …
Extracellular Vesicles in Therapeutics: A Comprehensive Review on Applications, Challenges, and Clinical Progress
Small Extracellular Vesicles (sEVs) are typically 30–150 nm in diameter, produced inside
cells, and released into the extracellular space. These vesicles carry RNA, DNA, proteins …
cells, and released into the extracellular space. These vesicles carry RNA, DNA, proteins …
Small extracellular vesicles as a new class of medicines
Extracellular vesicles (EVs) are nanovesicles that are naturally released from cells in a lipid
bilayer-bound form. A subset population with a size of 200 nm, small EVs (sEVs), is enticing …
bilayer-bound form. A subset population with a size of 200 nm, small EVs (sEVs), is enticing …
Small extracellular vesicles‐based cell‐free strategies for therapy
Small extracellular vesicles (sEVs) are extracellular nanovesicles that contain bioactive
proteins, lipids, RNA, and DNA. A variety of biological process is regulated with sEVs. sEVs …
proteins, lipids, RNA, and DNA. A variety of biological process is regulated with sEVs. sEVs …
[PDF][PDF] Biodistribution of therapeutic extracellular vesicles
D Gupta, OPB Wiklander, MJA Wood… - Extracell. Vesicles Circ …, 2023 - f.oaes.cc
The field of extracellular vesicles (EVs) has seen a tremendous paradigm shift in the past
two decades, from being regarded as cellular waste bags to being considered essential …
two decades, from being regarded as cellular waste bags to being considered essential …
Recent advancement and technical challenges in developing small extracellular vesicles for cancer drug delivery
T Geng, P Pan, E Leung, Q Chen, L Chamley… - Pharmaceutical …, 2021 - Springer
Extracellular vesicles (EVs) are a heterogeneous population of lipid bilayer membrane-
enclosed vesicles and act like 'messages in a bottle'in cell-cell communication by …
enclosed vesicles and act like 'messages in a bottle'in cell-cell communication by …
Extracellular vesicles: a rising star for therapeutics and drug delivery
S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …
Strategic design of extracellular vesicle drug delivery systems
JPK Armstrong, MM Stevens - Advanced drug delivery reviews, 2018 - Elsevier
Abstract Extracellular vesicles (EVs), sub-micron vectors used in intercellular
communication, have demonstrated great promise as natural drug delivery systems. Recent …
communication, have demonstrated great promise as natural drug delivery systems. Recent …
Small extracellular vesicle loading systems in cancer therapy: Current status and the way forward
YF Zhang, JB Shi, C Li - Cytotherapy, 2019 - Elsevier
Systemic chemotherapy is a conventional and important strategy for inhibition of cancer
progression, but it is usually accompanied by various adverse effects. Targeting drug …
progression, but it is usually accompanied by various adverse effects. Targeting drug …
Extracellular vesicles: powerful candidates in nano-drug delivery systems
X Liu, Y Cao, S Wang, J Liu, H Hao - Drug Delivery and Translational …, 2024 - Springer
Extracellular vesicles (EVs), which are nanoparticles that are actively released by cells,
contain a variety of biologically active substances, serve as significant mediators of …
contain a variety of biologically active substances, serve as significant mediators of …