The goal of this research was to find a new way to express native insect ion channels in
cultured cells for use in high throughput insecticide screening (HTS). A lepidopteran …

The aim of this study was to investigate the utility of cultured Anopheles gambiae Sua1B
cells for insecticide screening applications without genetic engineering or other treatments …

Voltage‐sensitive sodium channels encoded by the Vssc1 gene of the house fly (Musca
domestica) were expressed in Xenopus laevis oocytes in combination with the tipE gene …

Pyrethroid insecticides are neurotoxic to both insects and mammals. Most pyrethroids exhibit
low to moderate acute oral toxicity to mammals, but the intrinsic toxicity of pyrethroids, which …

Sodium channel blocker insecticides (SCBIs), such as indoxacarb and metaflumizone, are a
new class of insecticides with a mechanism of action different from those of other …

Two important insecticide target sites in the insect nervous system are the voltage-sensitive
sodium channel and the GABA (γ-aminobutyric acid) receptor/chloride ionophore complex. 1 …

Pyrethroid insecticides are classified as type I or type II based on their distinct symptomology
and effects on sodium channel gating. Structurally, type II pyrethroids possess an α-cyano …

Sodium channel inhibitor (SCI) insecticides were discovered almost four decades ago but
have only recently yielded important commercial products (eg, indoxacarb and …

Safe insecticides are essential if agriculture is to generate adequate supplies of high quality
food, maintain the health of farm animals and ensure that human populations secure …

Pyrethrin I, pyrethrin II, cinerin I, cinerin II, jasmolin I and jasmolin II are six closely related
insecticidal active esters, known as pyrethrins, found in the pyrethrum extract from the dry …