A Contemporary, Multifaced Insight into Psoriasis Pathogenesis

RC Dascălu, AL Bărbulescu, LE Stoica… - Journal of Personalized …, 2024 - mdpi.com
Psoriasis is a chronic recurrent inflammatory autoimmune pathology with a significant
genetic component and several interferences of immunological cells and their cytokines …

The molecular pathophysiology of psoriatic arthritis—the complex interplay between genetic predisposition, epigenetics factors, and the microbiome

AL Carvalho, CM Hedrich - Frontiers in molecular biosciences, 2021 - frontiersin.org
Psoriasis is a symmetric autoimmune/inflammatory disease that primarily affects the skin. In
a significant proportion of cases, it is accompanied by arthritis that can affect any joint, the …

[HTML][HTML] New frontiers in psoriatic disease research, part I: genetics, environmental triggers, immunology, pathophysiology, and precision medicine

D Yan, JE Gudjonsson, S Le, E Maverakis… - Journal of Investigative …, 2021 - Elsevier
Psoriasis is a chronic inflammatory condition characterized by systemic immune
dysregulation. Over the past several years, advances in genetics, microbiology …

Insights into interplay of immunopathophysiological events and molecular mechanistic cascades in psoriasis and its associated comorbidities

AK Srivastava, TC Yadav, HK Khera, P Mishra… - Journal of …, 2021 - Elsevier
Psoriasis is an inflammatory skin disease with complex pathogenesis and multiple
etiological factors. Besides the essential role of autoreactive T cells and constellation of …

Immune responses and therapeutic options in psoriasis

IS Afonina, E Van Nuffel, R Beyaert - Cellular and Molecular Life Sciences, 2021 - Springer
Psoriasis is a chronic inflammatory disease of the skin that affects about 2–3% of the
population and greatly impairs the quality of life of affected individuals. Psoriatic skin is …

Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis

JT Elder - Genes & Immunity, 2009 - nature.com
Psoriasis is a common, immunologically mediated, inflammatory and hyperproliferative
disease of the skin and joints, with a multifactorial genetic basis. We earlier mapped …

Inflammation and psoriasis: a comprehensive review

AM Man, MS Orăsan, OA Hoteiuc… - International Journal of …, 2023 - mdpi.com
Psoriasis is an immune-mediated disease with a strong genetic component that brings many
challenges to sick individuals, such as chronic illness, and which has multiple associated …

Roles of infection in psoriasis

S Zhou, Z Yao - International journal of molecular sciences, 2022 - mdpi.com
Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic
manifestations. Genetic predisposition, environmental factors, and immune dysfunction all …

Immunopathogenesis of psoriasis

P Di Meglio, FO Nestle - Clinical and basic immunodermatology, 2017 - Springer
Psoriasis is a common, complex, inflammatory skin disease resulting from the interplay of
genetic, environmental and immunological factors. In the last four decades, advances in …

Psoriasis: epidemiology, natural history, and differential diagnosis

JL Basko-Plluska, V Petronic-Rosic - Psoriasis: Targets and …, 2012 - Taylor & Francis
Psoriasis is a chronic, immune-mediated, inflammatory disease which affects primarily the
skin and joints. It occurs worldwide, but its prevalence varies considerably between different …