Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities
Yeast is an integral part of mammalian microbiome, and like commensal bacteria, has the
potential of being harnessed to influence immunity in clinical settings. However, functional …
potential of being harnessed to influence immunity in clinical settings. However, functional …
Molecular analysis of a short-term model of β-glucans-trained immunity highlights the accessory contribution of GM-CSF in priming mouse macrophages response
S Walachowski, G Tabouret, M Fabre… - Frontiers in …, 2017 - frontiersin.org
β-Glucans (BGs) are glucose polymers present in the fungal cell wall (CW) and, as such, are
recognized by innate immune cells as microbial-associated pattern through Dectin-1 …
recognized by innate immune cells as microbial-associated pattern through Dectin-1 …
New insight into the structure-dependent two-way immunomodulatory effects of water-soluble yeast β-glucan in macrophages
Z Zheng, Q Huang - Carbohydrate Polymers, 2022 - Elsevier
The immunomodulatory effects and signalling pathways of five water-soluble yeast β-glucan
fractions (WYG1–5) with different molecular weights (M w) and chain conformations were …
fractions (WYG1–5) with different molecular weights (M w) and chain conformations were …
Triggering dectin-1-pathway alone is not sufficient to induce cytokine production by murine macrophages
S Walachowski, G Tabouret, G Foucras - PloS one, 2016 - journals.plos.org
β-glucans (BG) are abundant polysaccharides of the Saccharomyces cerevisiae cell wall (Sc
CW), an industry byproduct. They have immuno-stimulatory properties upon engagement of …
CW), an industry byproduct. They have immuno-stimulatory properties upon engagement of …
Candida albicans β-Glucan Differentiates Human Monocytes Into a Specific Subset of Macrophages
J Leonhardt, S Große, C Marx, F Siwczak… - Frontiers in …, 2018 - frontiersin.org
β-Glucan derived from cell walls of Candida albicans is a potent immune modulator. It has
been shown to induce trained immunity in monocytes via epigenetic and metabolic …
been shown to induce trained immunity in monocytes via epigenetic and metabolic …
LC3-Associated Phagocytosis Is Required for Dendritic Cell Inflammatory Cytokine Response to Gut Commensal Yeast Saccharomyces cerevisiae
D Lamprinaki, G Beasy, A Zhekova… - Frontiers in …, 2017 - frontiersin.org
The human fungal microbiota known as mycobiota is increasingly recognized as a critical
factor in human gut health and disease. Non-pathogenic commensal yeasts such as …
factor in human gut health and disease. Non-pathogenic commensal yeasts such as …
Complex dietary polysaccharide modulates gut immune function and microbiota, and promotes protection from autoimmune diabetes
The dietary supplement and prebiotic values of β‐glucan‐rich products have been widely
recognized and dietary approaches for modulating autoimmunity have been increasingly …
recognized and dietary approaches for modulating autoimmunity have been increasingly …
A drug-sensitive genetic network masks fungi from the immune system
RT Wheeler, GR Fink - PLoS pathogens, 2006 - journals.plos.org
Fungal pathogens can be recognized by the immune system via their β-glucan, a potent
proinflammatory molecule that is present at high levels but is predominantly buried beneath …
proinflammatory molecule that is present at high levels but is predominantly buried beneath …
Brewer's yeast polysaccharides—a review of their exquisite structural features and biomedical applications
Recent advances on brewer's yeast cell wall polysaccharides have unraveled exquisite
structural features and diverse composition with (β1→ 3),(β1→ 6),(α1→ 4),(β 1→ 4)-mix …
structural features and diverse composition with (β1→ 3),(β1→ 6),(α1→ 4),(β 1→ 4)-mix …
Inhibition of dextran sodium sulfate-induced colitis in mice by baker's yeast polysaccharides
Y Sun, X Shi, X Zheng, S Nie, X Xu - Carbohydrate polymers, 2019 - Elsevier
Most of the reported yeast polysaccharides are a mixture of chitin, β-glucan and
mannoprotein, leading to different biological activities. Herein, we report the structures and …
mannoprotein, leading to different biological activities. Herein, we report the structures and …
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