Zebrafish: an emerging real-time model system to study Alzheimer's disease and neurospecific drug discovery
S Saleem, RR Kannan - Cell death discovery, 2018 - nature.com
Zebrafish (Danio rerio) is emerging as an increasingly successful model for translational
research on human neurological disorders. In this review, we appraise the high degree of …
research on human neurological disorders. In this review, we appraise the high degree of …
Zebrafish as a model organism for neurodegenerative disease
K Chia, A Klingseisen, D Sieger… - Frontiers in molecular …, 2022 - frontiersin.org
The zebrafish is increasingly recognized as a model organism for translational research into
human neuropathology. The zebrafish brain exhibits fundamental resemblance with human …
human neuropathology. The zebrafish brain exhibits fundamental resemblance with human …
Zebrafish and medaka: important animal models for human neurodegenerative diseases
J Wang, H Cao - International journal of molecular sciences, 2021 - mdpi.com
Animal models of human neurodegenerative disease have been investigated for several
decades. In recent years, zebrafish (Danio rerio) and medaka (Oryzias latipes) have become …
decades. In recent years, zebrafish (Danio rerio) and medaka (Oryzias latipes) have become …
Modeling neurodegeneration in zebrafish
Y Xi, S Noble, M Ekker - Current neurology and neuroscience reports, 2011 - Springer
The zebrafish, Danio rerio, has been established as an excellent vertebrate model for the
study of developmental biology and gene function. It also has proven to be a valuable model …
study of developmental biology and gene function. It also has proven to be a valuable model …
Advances of zebrafish in neurodegenerative disease: from models to drug discovery
X Wang, JB Zhang, KJ He, F Wang… - Frontiers in Pharmacology, 2021 - frontiersin.org
Neurodegenerative disease (NDD), including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …
Zebrafish models for translational neuroscience research: from tank to bedside
The zebrafish (Danio rerio) is emerging as a new important species for studying
mechanisms of brain function and dysfunction. Focusing on selected central nervous system …
mechanisms of brain function and dysfunction. Focusing on selected central nervous system …
Modeling neurodegenerative disorders in zebrafish
AA Bashirzade, KN Zabegalov, AD Volgin… - Neuroscience & …, 2022 - Elsevier
Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …
Zebrafish—a model organism for studying the neurobiological mechanisms underlying cognitive brain aging and use of potential interventions
MM Adams, H Kafaligonul - Frontiers in cell and developmental …, 2018 - frontiersin.org
Classically, the zebrafish model organism has been used to elucidate the genetic and
cellular mechanisms related to development since the embryo forms and grows externally …
cellular mechanisms related to development since the embryo forms and grows externally …
Using the zebrafish model for Alzheimer's disease research
Rodent models have been extensively used to investigate the cause and mechanisms
behind Alzheimer's disease. Despite many years of intensive research using these models …
behind Alzheimer's disease. Despite many years of intensive research using these models …
Advances in zebrafish as a comprehensive model of mental disorders
L Wang, F Liu, Y Fang, J Ma, J Wang, L Qu… - Depression and …, 2023 - Wiley Online Library
As an important part in international disease, mental disorders seriously damage human
health and social stability, which show the complex pathogenesis and increasing incidence …
health and social stability, which show the complex pathogenesis and increasing incidence …