Maternal obesity is associated with placental lipotoxicity, oxidative stress, and inflammation,
where MAPK activity may play a central role. Accordingly, we have previously shown that …

Obesity is associated with low-grade chronic inflammation, which contributes to cellular
dysfunction promoting metabolic disease. Obesity during pregnancy leads to a …

Maternal obesity is associated with placental oxidative stress. However, the mechanism
underlying this association remains poorly understood. In the present study, a gilt obesity …

Increasing maternal obesity is a challenge that has an impact on all aspects of female
reproduction. Lean and obese pregnant women gain similar fat mass, but lean women store …

Maternal obesity is an increasing problem in obstetrics associated with adverse pregnancy
outcomes and delivery complications. As an inflammatory state, where elevated levels of pro …

Objective To determine oxidative stress markers in maternal obesity during pregnancy and
to evaluate feto-placental unit interaction, especially predictors of fetal metabolic alterations …

Aim The current study investigated the impact of maternal obesity on placental phenotype in
relation to fetal growth and sex. Methods Female C57BL6/J mice were fed either a diet high …

Metabolic impairments in maternal obesity and gestational diabetes mellitus (GDM) induce
an abnormal environment in peripheral blood and cause vascular structure alterations which …

It is well-accepted that maternal obesity affects fetal development to elevate the risk of
offspring disease, but how this happens is unclear. Understanding placental alterations …

Maternal obesity has a major impact on pregnancy outcomes. There is growing evidence
that maternal obesity has a negative influence on placental development and function …