Bi-layer silk fibroin skeleton and bladder acellular matrix hydrogel encapsulating adipose-derived stem cells for bladder reconstruction

S Xiao, P Wang, J Zhao, Z Ling, Z An, Z Fu, W Fu… - Biomaterials …, 2021 - pubs.rsc.org
A scaffold, constructed from a bi-layer silk fibroin skeleton (BSFS) and a bladder acellular
matrix hydrogel (BAMH) encapsulated with adipose-derived stem cells (ASCs), was …

[HTML][HTML] Adipose-derived stem cells-seeded bladder acellular matrix graft-silk fibroin enhances bladder reconstruction in a rat model

D Xiao, Q Wang, H Yan, X Lv, Y Zhao, Z Zhou… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The unfavourable clinical outcomes of host cell-seeded scaffolds for bladder augmentation
warrant improved bioactive biomaterials. This study aimed to examine the feasibility of …

Time-dependent bladder tissue regeneration using bilayer bladder acellular matrix graft-silk fibroin scaffolds in a rat bladder augmentation model

Y Zhao, Y He, J Guo, J Wu, Z Zhou, M Zhang, W Li… - Acta biomaterialia, 2015 - Elsevier
With advances in tissue engineering, various synthetic and natural biomaterials have been
widely used in tissue regeneration of the urinary bladder in rat models. However …

The morphological regeneration and functional restoration of bladder defects by a novel scaffold and adipose-derived stem cells in a rat augmentation model

Q Wang, D Xiao, H Yan, Y Zhao, S Fu, J Zhou… - Stem cell research & …, 2017 - Springer
Background Due to the multilineage differentiation ability and paracrine role of adipose-
derived stem cells (ASCs) for bladder defect repair, various scaffolds have been applied in …

Trilayer three-dimensional hydrogel composite scaffold containing encapsulated adipose-derived stem cells promotes bladder reconstruction via SDF-1α/CXCR4 …

D Xiao, H Yan, Q Wang, X Lv, M Zhang… - … applied materials & …, 2017 - ACS Publications
Bladder acellular matrix graft-alginate dialdehyde-gelatin hydrogel-silk mesh (BAMG-HS)
encapsulated with adipose-derived stem cells (ASCs) was evaluated in a rat model of …

Bioengineered bladder patches constructed from multilayered adipose-derived stem cell sheets for bladder regeneration

Y Wang, S Zhou, R Yang, Q Zou, K Zhang, Q Tian… - Acta Biomaterialia, 2019 - Elsevier
Cell-seeded scaffolds are a common route of cell transplantation for bladder repair and
reconstruction. However, when cell suspensions are harvested, proteolytic enzymes often …

Transplantation of human adipose-derived mesenchymal stem cells on a bladder acellular matrix for bladder regeneration in a canine model

X Hou, C Shi, W Chen, B Chen, W Jia, Y Guo… - Biomedical …, 2016 - iopscience.iop.org
Tissue engineering brings new hope for the reconstruction of injured bladders. The aim of
the present study was to evaluate human adipose-derived mesenchymal stem cells …

Differentiation of human endometrial stem cells into urothelial cells on a three‐dimensional nanofibrous silk–collagen scaffold: an autologous cell resource for …

A Shoae‐Hassani… - Journal of tissue …, 2015 - Wiley Online Library
Reconstruction of the bladder wall via in vitro differentiated stem cells on an appropriate
scaffold could be used in such conditions as cancer and neurogenic urinary bladder. This …

[HTML][HTML] Bladder acellular matrix prepared by a self-designed perfusion system and adipose-derived stem cells to promote bladder tissue regeneration

S Xiao, P Wang, J Zhao, Z Ling, Z An, Z Fu… - … in Bioengineering and …, 2022 - frontiersin.org
The bladder patch constructed with the bladder acellular matrix (BAM) and adipose-derived
stem cells (ASCs) was incubated with the omentum for bladder reconstruction in a rat model …

Sustained release of stromal cell–derived factor‐1 alpha from silk fibroin microfiber promotes urethral reconstruction in rabbits

Y Liu, L Huang, W Yuan, D Zhang, Y Gu… - … Research Part A, 2020 - Wiley Online Library
We developed a stromal cell–derived factor‐1 alpha (SDF‐1α)‐aligned silk fibroin (SF)/three‐
dimensional porous bladder acellular matrix graft (3D‐BAMG) composite scaffold for long …