Interstitial null-distance time-domain diffuse optical spectroscopy using a superconducting nanowire detector

V Damagatla, P Lanka, A Brodu… - Journal of …, 2023 - spiedigitallibrary.org
Significance Interstitial fiber-based spectroscopy is gaining interest for real-time in vivo
optical biopsies, endoscopic interventions, and local monitoring of therapy. Different from …

Single-fiber diffuse optical time-of-flight spectroscopy

E Alerstam, T Svensson, S Andersson-Engels… - Optics letters, 2012 - opg.optica.org
We demonstrate interstitial diffuse optical time-of-fight spectroscopy based on a single fiber
for both light delivery and detection. Detector saturation due to the massive short-time …

Fast time-domain diffuse correlation spectroscopy with superconducting nanowire single-photon detector: system validation and in vivo results

V Parfentyeva, L Colombo, P Lanka, M Pagliazzi… - Scientific Reports, 2023 - nature.com
Time-domain diffuse correlation spectroscopy (TD-DCS) has been introduced as an
advancement of the “classical” continuous wave DCS (CW-DCS) allowing one to not only to …

Use of bioresorbable fibers for short-wave infrared spectroscopy using time-domain diffuse optics

V Damagatla, NG Boetti, L Di Sieno… - Biomedical Optics …, 2024 - opg.optica.org
We demonstrate the usability of bioresorbable phosphate glass fibers for time-domain
diffuse optical spectroscopy (TD-DOS) in the short-wave infrared (SWIR) region of 950–1600 …

Multi-distance diffuse optical spectroscopy with a single optode via hypotrochoidal scanning

MB Applegate, D Roblyer - Optics letters, 2018 - opg.optica.org
Frequency-domain diffuse optical spectroscopy (FD-DOS) is an established technique
capable of determining optical properties and chromophore concentrations in biological …

First-in-clinical application of a time-gated diffuse correlation spectroscopy system at 1064 nm using superconducting nanowire single photon detectors in a neuro …

CS Poon, DS Langri, B Rinehart, TM Rambo… - Biomedical Optics …, 2022 - opg.optica.org
Recently proposed time-gated diffuse correlation spectroscopy (TG-DCS) has significant
advantages compared to conventional continuous wave (CW)-DCS, but it is still in an early …

Instrument response function acquisition in reflectance geometry for time-resolved diffuse optical measurements

I Pirovano, R Re, A Candeo, D Contini… - Biomedical Optics …, 2019 - opg.optica.org
In time-domain diffuse optical spectroscopy, the simultaneous acquisition of the time-of-flight
distribution (DTOF) of photons traveling in a diffusive medium and of the instrument …

Dual-slope method for enhanced depth sensitivity in diffuse optical spectroscopy

A Sassaroli, G Blaney, S Fantini - JOSA A, 2019 - opg.optica.org
Using diffusion theory, we show that a dual-slope method is more effective than single-slope
methods or single-distance methods at enhancing sensitivity to deeper tissue. The dual …

Fast silicon photomultiplier improves signal harvesting and reduces complexity in time-domain diffuse optics

AD Mora, E Martinenghi, D Contini, A Tosi, G Boso… - Optics express, 2015 - opg.optica.org
We present a proof of concept prototype of a time-domain diffuse optics probe exploiting a
fast Silicon PhotoMultiplier (SiPM), featuring a timing resolution better than 80 ps, a fast tail …

Cross-wavelength calibrating method for real-time imaging of tissue optical properties using frequency-domain diffuse optical spectroscopy

T Pham, LL Wei, D Roblyer - Biomedical Optics Express, 2024 - opg.optica.org
Frequency-domain diffuse optical spectroscopy (FD-DOS) is a powerful non-invasive
technique for assessing tissue optical properties, with applications ranging from basic …