Liver regeneration

N Fausto - Journal of hepatology, 2000 - Elsevier
The liver can precisely regulate its growth and mass. Surgical resection of hepatic lobes or
hepatocyte loss caused by viral or chemical injury triggers hepatocyte replication while …

[PDF][PDF] Liver regeneration

N Fausto, JS Campbell, KJ Riehle - Hepatology, 2006 - Wiley Online Library
During liver regeneration after partial hepatectomy, normally quiescent hepatocytes undergo
one or two rounds of replication to restore the liver mass by a process of compensatory …

Liver development and regeneration: from laboratory study to clinical therapy

S Hata, M Namae, H Nishina - Development, growth & …, 2007 - Wiley Online Library
The liver has an unusual capacity to regenerate after a loss of mass and function caused by
surgical resection or toxic liver injury. Over the last 10 years there have been major …

Role of growth factors and cytokines in hepatic regeneration

N Fausto, AD Laird, EM Webber - The FASEB Journal, 1995 - Wiley Online Library
During liver regeneration quiescent hepatocytes undergo one or two rounds of replication
and then return to a nonproliferative state. Growth factors regulate this process by providing …

Understanding the marvels behind liver regeneration

A Abu Rmilah, W Zhou, E Nelson, L Lin… - Wiley …, 2019 - Wiley Online Library
Tissue regeneration is a process by which the remaining cells of an injured organ regrow to
offset the missed cells. This field is relatively a new discipline that has been a focus of …

Transcriptional control of liver regeneration

R Taub - The FASEB Journal, 1996 - Wiley Online Library
Determining what factors are responsible for initiating regeneration following partial
hepateetomy or toxic damage, and how the liver maintains differentiated functions while the …

[HTML][HTML] Signals and cells involved in regulating liver regeneration

LI Kang, WM Mars, GK Michalopoulos - Cells, 2012 - mdpi.com
Liver regeneration is a complex phenomenon aimed at maintaining a constant liver mass in
the event of injury resulting in loss of hepatic parenchyma. Partial hepatectomy is followed …

Advances in liver regeneration

GK Michalopoulos - Expert review of gastroenterology & …, 2014 - Taylor & Francis
Liver regeneration after partial hepatectomy is the only example of a regenerative process in
mammals in which the organ/body weight ratio returns to 100% of the original when the …

Liver regeneration: the emergence of new pathways.

A Zimmermann - … science monitor: international medical journal of …, 2002 - europepmc.org
The present overview summarizes important knowledge having accumulated during the last
years. The liver maintains a steady mass which is basically controlled by a delicate balance …

[HTML][HTML] Understanding liver regeneration: from mechanisms to regenerative medicine

H Gilgenkrantz, AC de l'Hortet - The American journal of pathology, 2018 - Elsevier
Liver regeneration is a complex and unique process. When two-thirds of a mouse liver is
removed, the remaining liver recovers its initial weight in approximately 10 days. The …