Liver transplantation is increasingly dependent on the use of extended criteria donors (ECD)
to increase the organ donor pool and address rising demand. This has necessitated the …

Abstract Purpose of Review This review aims to introduce the concept of normothermic
machine perfusion (NMP) and its role in liver transplantation. By discussing results from …

Machine perfusion (MP) preservation is potentially one of the most significant improvements
in the field of liver transplantation in the last 20 years, and it has been considered a …

Donor organ shortage necessitates use of less than optimal donor allografts for
transplantation. The current cold storage preservation technique fails to preserve marginal …

A shortage of available organs for liver transplantation has led transplant surgeons and
researchers to seek for innovative approaches in hepatoprotection and improvement of …

Objective: Normothermic machine perfusion (NMP) enables optimized ex-vivo preservation
of a donor liver in a normal physiologic state. The impact of this emerging technology on …

Longstanding research describes the mechanisms whereby the restoration of blood flow
and reoxygenation (reperfusion) aggravates the ischaemic injury caused by a period of …

In the face of a critical organ shortage in the Western world, various strategies are employed
to expand the donor pool for orthotopic liver transplantation (OLT). Among them is the …

Liver transplantation has become an immense success; nevertheless, far more recipients
are registered on waiting lists than there are available donor livers for transplantation. High …

In recent years, there has been growing interest in normothermic machine perfusion (NMP)
as a preservation method in liver transplantation. In most countries, because of a donor …