Background Inflammation during brain development participates in the pathogenesis of
early brain injury and cognitive dysfunctions. Prenatal ethanol exposure affects the …

Fetal alcohol spectrum disorders (FASD) are alarmingly common and result in significant
personal and societal loss. Neuropathology of the hippocampus is common in FASD leading …

Background Fetal alcohol exposure is a leading cause of preventable birth defects, yet
drinking during pregnancy remains prevalent worldwide. Studies suggest that activation of …

During early brain development, microglial activation can negatively impact long-term
neuroimmune and cognitive outcomes. It is well-known that significant alcohol exposure …

Fetal alcohol spectrum disorders (FASD) are alarmingly common, result in significant
personal and societal loss, and there is no effective treatment for these disorders. Cerebellar …

The adolescent brain undergoes important dynamic and plastic cell changes, including
overproduction of axons and synapses, followed by rapid pruning along with ongoing axon …

The behavioral consequences of fetal alcohol spectrum disorders (FASD) are serious and
persist throughout life. The causative mechanisms underlying FASD are poorly understood …

Studies in humans and experimental animals have demonstrated the vulnerability of the
adolescent brain to actions of ethanol and the long-term consequences of binge drinking …

Fetal alcohol spectrum disorders (FASD) constitute a wide range of disorders that arise from
prenatal exposure to ethanol (EtOH). However, detailed reports regarding the adverse …

Ethanol induces neurodegeneration in the developing brain, which may partially explain the
long-lasting adverse effects of prenatal ethanol exposure in fetal alcohol spectrum disorders …