A novel method for crystallization utilizing solvent/antisolvent extraction in microfluidic
droplet liquid reactors has been developed for rapid and low-cost screening of crystal …

In this work, an innovative experimental platform to study the nucleation behavior of an
active pharmaceutical ingredient (API) using a gas-segmented flow produced by a …

A microfluidic approach to seeded crystallization has been demonstrated using abacavir
hemisulfate, a nucleoside analog reverse transcriptase inhibitor, in droplet reactors to …

In this paper, we demonstrate a continuous flow evaporative crystallization platform for
producing monodisperse microparticles containing crystalline API with tunable particle sizes …

Crystallization is one of the most crucial steps in the process of pharmaceutical formulation.
In recent years, emulsion-based platforms have been developed and broadly adopted to …

Granulation is a common manufacturing step for pharmaceutical drug products, which
improves powder flowability, compactibility, and ensures tablet content uniformity. Granules …

Emulsion-based crystallization to produce spherical crystalline agglomerates (SAs) is an
attractive route to control crystal size during downstream processing of active …

We describe a microfluidic approach to optimize crystallization of active pharmaceutical
ingredients (APIs) and their solid forms (cocrystals) via crystal seeding. Subsequent on-chip …

This thesis presents one of the first demonstrations of continuous crystallization in
microfluidic devices, and illustrates their use for various applications related to crystallization …

A novel continuous fluidic method based on extractive crystallization for producing
monodisperse spherical crystal aggregates with potential use in pharmaceutical …