Background A significant proportion of donation after circulatory death (DCD) kidneys are
declined for transplantation because of concerns over their quality. Ex vivo normothermic …

Background A significant proportion of kidneys procured for transplantation are discarded
because of concerns about their suitability. In this study ex vivo normothermic perfusion …

Machine perfusion for preservation led to compelling success for the outcome of renal
transplantation. Further refinements of methods to decrease preservation injury remain an …

Introduction Ex vivo normothermic perfusion (EVNP) is a novel technique that reconditions
the kidney and restores renal function prior to transplantation. Phase I data from a series of …

BACKGROUND: Hypothermic machine perfusion (HMP) of kidneys is intended to mitigate
the deleterious effects of cold storage on organ quality, particularly when the cold ischemic …

Kidney transplantation is the optimal treatment for end-stage renal disease, but it is still
severely limited by a lack of suitable organ donors. Kidneys from donation after circulatory …

We report the successful transplantation of a pair of human kidneys that were declined for
transplantation due to inadequate in situ perfusion but subsequently transplanted after …

Background The 5-year graft survival rate of donor kidneys transplanted in the
Eurotransplant Senior Program (ESP) is only 47 per cent. Normothermic machine perfusion …

Background Many kidneys are rejected for transplantation due to inadequate in situ
perfusion during organ retrieval because of the risk of additional ischaemic injury and …

Hypothermic machine perfusion (HMP) of kidneys is a long‐established alternative to static
cold storage and has been suggested to be a better preservation method. Today, as our …