Pulmonary aerosol transport and deposition analysis in upper 17 generations of the human respiratory tract

MS Islam, SC Saha, E Sauret, T Gemci, YT Gu - Journal of Aerosol Science, 2017 - Elsevier
The major problem in understanding the therapeutically targeted drug delivery system in the
deeper airways of the human lung is the lack of adequate data of particle transport and …

[HTML][HTML] A review of respiratory anatomical development, air flow characterization and particle deposition

MS Islam, G Paul, HX Ong, PM Young, YT Gu… - International journal of …, 2020 - mdpi.com
The understanding of complex inhalation and transport processes of pollutant particles
through the human respiratory system is important for investigations into dosimetry and …

CFD simulation of aerosol deposition in an anatomically based human large–medium airway model

B Ma, KR Lutchen - Annals of biomedical engineering, 2009 - Springer
Quantitative data on aerosol deposition in the human respiratory tract are useful for
understanding the causes of certain lung diseases and for designing efficient drug delivery …

Aging effects on airflow distribution and micron-particle transport and deposition in a human lung using CFD-DPM approach

MM Rahman, M Zhao, MS Islam, K Dong… - Advanced Powder …, 2021 - Elsevier
Understanding the transportation and deposition (TD) of inhaled aerosol particles in human
lung airways is important for health risk assessment and therapeutic efficiency of targeted …

[HTML][HTML] Nanoparticle transport and deposition in a heterogeneous human lung airway tree: An efficient one path model for CFD simulations

MM Rahman, M Zhao, MS Islam, K Dong… - European Journal of …, 2022 - Elsevier
Understanding nano-particle inhalation in human lung airways helps targeted drug delivery
for treating lung diseases. A wide range of numerical models have been developed to …

Numerical study of nano and micro pollutant particle transport and deposition in realistic human lung airways

M Rahman, M Zhao, MS Islam, K Dong, SC Saha - Powder Technology, 2022 - Elsevier
For respiratory health risk assessment, it is essential to evaluate the transportation and
deposition (TD) of pollutant particles in human lung airways, which are responsible for lung …

Three-dimensional computational fluid dynamics simulations of particle deposition in the tracheobronchial tree

KK Isaacs, RB Schlesinger… - Journal of aerosol …, 2006 - liebertpub.com
Simulation of the dynamics and disposition of inhaled particles within human lungs is an
invaluable tool in both the development of inhaled pharmacologic drugs and the risk …

Numerical study of nanoscale and microscale particle transport in realistic lung models with and without stenosis

MM Rahman, M Zhao, MS Islam, K Dong… - International Journal of …, 2021 - Elsevier
The transport and deposition (TD) of inhaled aerosol particles in airways of human lungs are
important for therapeutically targeted drug delivery in respiratory tracts. The airflow and …

Comparison of analytical and CFD models with regard to micron particle deposition in a human 16-generation tracheobronchial airway model

Z Zhang, C Kleinstreuer, CS Kim - Journal of Aerosol Science, 2009 - Elsevier
A representative human tracheobronchial tree has been geometrically represented with
adjustable triple-bifurcation units (TBUs) in order to effectively simulate local and global …

Current inhalers deliver very small doses to the lower tracheobronchial airways: assessment of healthy and constricted lungs

RL Walenga, PW Longest - Journal of pharmaceutical sciences, 2016 - Elsevier
To evaluate the regional delivery of conventional aerosol medications, a new whole-lung
computational fluid dynamics modeling approach was applied for metered dose inhaler …