Stage-specific quantitative changes in renal and urinary proteome during the progression and development of streptozotocin-induced diabetic nephropathy in rats

V Sharma, K Tikoo - Molecular and cellular biochemistry, 2014 - Springer
Diabetic nephropathy (DN) is a microvascular complication associated with diabetes
causing slow deterioration of kidneys leading to end-stage renal disease. Timely …

Proteome analysis of altered proteins in streptozotocin‐induced diabetic rat kidney using the fluorogenic derivatization–liquid chromatography–tandem mass …

PY Tsai, SM Chen, HY Chen, YC Li… - Biomedical …, 2013 - Wiley Online Library
To find new molecular markers for early diagnosis of diabetic nephropathy, we applied
fluorogenic derivatization–liquid chromatography–tandem mass spectrometry to identify the …

Potential biomarkers associated with diabetic glomerulopathy through proteomics

YC Hsu, CC Lei, C Ho, YH Shih, CL Lin - Renal Failure, 2015 - Taylor & Francis
Diabetic nephropathy (DN) is characterized by the development of progressive
glomerulosclerotic lesions gradually leading to an increasing loss of functioning kidney …

Differential expression of proteins in kidney, eye, aorta, and serum of diabetic and non‐diabetic rats

WC Cho, TT Yip, WS Chung, AW Leung… - Journal of cellular …, 2006 - Wiley Online Library
Diabetes mellitus (DM) is a chronic progressive disease that often results in microvascular
and macrovascular complications, yet its pathogenesis is not clear. Automated proteomic …

Proteomic analysis of early urinary biomarkers of renal changes in type 2 diabetic patients

E Bellei, E Rossi, L Lucchi, S Uggeri… - PROTEOMICS …, 2008 - Wiley Online Library
Diabetic nephropathy (DN) is a complication associated with diabetes, leading to end‐stage
renal disease (ESRD). Despite significant progress in understanding DN, the cellular …

[HTML][HTML] Proteomic and bioinformatic discovery of biomarkers for diabetic nephropathy

C Thippakorn, N Schaduangrat, C Nantasenamat - EXCLI journal, 2018 - ncbi.nlm.nih.gov
Diabetes is associated with numerous metabolic and vascular risk factors that contribute to a
high rate of micro-vascular and macro-vascular disorders leading to mortality and morbidity …

[HTML][HTML] Characterization of low molecular weight urinary proteins at varying time intervals in type 2 diabetes mellitus and diabetic nephropathy patients

DN Patel, K Kalia - Diabetology & Metabolic Syndrome, 2019 - Springer
Background To identify low molecular weight urinary proteins capable of detecting diabetic
nephropathy patients which may predict renal alterations at early stages and prevent it from …

Proteome analysis of serum from type 2 diabetics with nephropathy

HJ Kim, EH Cho, JH Yoo, PK Kim, JS Shin… - Journal of proteome …, 2007 - ACS Publications
Diabetic nephropathy (DN) is a renal disease which develops as a consequence of diabetes
mellitus. Microalbuminuria is the earliest clinical sign of DN. There are no specific diagnostic …

[HTML][HTML] Proteomic profile in glomeruli of type-2 diabetic KKAy mice using 2-dimensional differential gel electrophoresis

X Liu, G Yang, Q Fan, L Wang - Medical Science Monitor …, 2014 - ncbi.nlm.nih.gov
Background Diabetic nephropathy (DN) is a leading cause of end-stage renal disease. To
search for glomerular proteins associated with early-stage DN, glomeruli of spontaneous …

[HTML][HTML] Identification of novel biomarker for early detection of diabetic nephropathy

KS Kim, JS Lee, JH Park, EY Lee, JS Moon, SK Lee… - Biomedicines, 2021 - mdpi.com
Diabetic nephropathy (DN) is one of the most common complications of diabetes mellitus.
After development of DN, patients will progress to end-stage renal disease, which is …