[HTML][HTML] TERT promoter mutations in thyroid cancer
R Liu, M Xing - Endocrine-related cancer, 2016 - erc.bioscientifica.com
The 2013 discovery of Telomerase reverse transcriptase (TERT) promoter mutations chr5,
1,295,228 C> T (C228T) and 1,295,250 C> T (C250T) in thyroid cancer represents an …
1,295,228 C> T (C228T) and 1,295,250 C> T (C250T) in thyroid cancer represents an …
Frequent Somatic TERT Promoter Mutations in Thyroid Cancer: Higher Prevalence in Advanced Forms of the Disease
Background: TERT encodes the reverse transcriptase component of telomerase, which adds
telomere repeats to chromosome ends, thus enabling cell replication. Telomerase activity is …
telomere repeats to chromosome ends, thus enabling cell replication. Telomerase activity is …
TERT promoter mutations and long-term survival in patients with thyroid cancer
TH Kim, YE Kim, S Ahn, JY Kim, CS Ki… - Endocr Relat …, 2016 - erc.bioscientifica.com
TERT promoter mutations are emerging prognostic biomarkers in multiple cancers and are
found in highly aggressive thyroid cancer. Our aim is to investigate the prognostic value of …
found in highly aggressive thyroid cancer. Our aim is to investigate the prognostic value of …
[HTML][HTML] Highly prevalent TERT promoter mutations in aggressive thyroid cancers
Abstract Mutations 1 295 228 C> T and 1 295 250 C> T (termed C228T and C250T
respectively), corresponding to− 124 C> T and− 146 C> T from the translation start site in the …
respectively), corresponding to− 124 C> T and− 146 C> T from the translation start site in the …
[HTML][HTML] TERT Promoter Mutations in Thyroid Cancer
Two mutations (C228T and C250T) in the promoter region of the telomerase reverse
transcriptase (TERT) have recently been described in different types of cancer including …
transcriptase (TERT) have recently been described in different types of cancer including …
TERT Promoter Mutations and Their Association with BRAF V600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer
Context: Promoter mutations chr5: 1,295,228 C> T and chr5: 1,295,250 C> T (termed C228T
and C250T, respectively) in the gene for telomerase reverse transcriptase (TERT) have …
and C250T, respectively) in the gene for telomerase reverse transcriptase (TERT) have …
Prognostic effects of TERT promoter mutations are enhanced by coexistence with BRAF or RAS mutations and strengthen the risk prediction by the ATA or TNM …
YS Song, JA Lim, H Choi, JK Won, JH Moon, SW Cho… - Cancer, 2016 - Wiley Online Library
BACKGROUND Recent reports suggest that mutations in the promoter of the gene encoding
telomerase reverse transcriptase (TERT) affect thyroid cancer outcomes. METHODS In all …
telomerase reverse transcriptase (TERT) affect thyroid cancer outcomes. METHODS In all …
[HTML][HTML] ETS fusion genes in prostate cancer
DG Tandefelt, J Boormans, K Hermans… - Endocrine-related …, 2014 - erc.bioscientifica.com
The 2013 discovery of Telomerase reverse transcriptase (TERT) promoter mutations chr5,
1,295,228 C> T (C228T) and 1,295,250 C> T (C250T) in thyroid cancer represents an …
1,295,228 C> T (C228T) and 1,295,250 C> T (C250T) in thyroid cancer represents an …
[HTML][HTML] TERT promoter mutations identify a high-risk group in metastasis-free advanced thyroid carcinoma
C Bournaud, F Descotes, M Decaussin-Petrucci… - European Journal of …, 2019 - Elsevier
Background TERT promoter mutations are associated with adverse clinicopathological
characteristics in thyroid carcinomas and considered as a major indicator of poor outcomes …
characteristics in thyroid carcinomas and considered as a major indicator of poor outcomes …
Prognostic Significance of TERT Promoter Mutations in Papillary Thyroid Carcinomas in a BRAFV600E Mutation–Prevalent Population
Background: The role of telomerase reverse transcriptase (TERT) promoter mutations in
differentiated thyroid cancer has been well established. These mutations have a significantly …
differentiated thyroid cancer has been well established. These mutations have a significantly …