Transcriptomics‐Based Points of Departure for Daphnia magna Exposed to 18 Per‐ and Polyfluoroalkyl Substances

DL Villeneuve, BR Blackwell, K Bush… - Environmental …, 2024 - Wiley Online Library
Per‐and polyfluoroalkyl substances (PFAS) represent a large group of contaminants of
concern based on their widespread use, environmental persistence, and potential toxicity …

Sublethal Exposure of Per‐and Polyfluoroalkyl Substances of Varying Chain Length and Polar Functionality Results in Distinct Metabolic Responses in Daphnia …

LM Labine, EA Oliveira Pereira… - Environmental …, 2023 - Wiley Online Library
Per‐and polyfluoroalkyl substances (PFAS) are a class of persistent organic pollutants used
in industrial applications because of their physicochemical properties, which results in their …

Derivation of Transcriptomics‐Based Points of Departure for 20 Per‐ or Polyfluoroalkyl Substances Using a Larval Fathead Minnow (Pimephales promelas) Reduced …

DL Villeneuve, K Bush, M Hazemi… - Environmental …, 2024 - Wiley Online Library
Traditional toxicity testing has been unable to keep pace with the introduction of new
chemicals into commerce. Consequently, there are limited or no toxicity data for many …

Comparison of sub-lethal metabolic perturbations of select legacy and novel perfluorinated alkyl substances (PFAS) in Daphnia magna

LM Labine, EAO Pereira, S Kleywegt, KJ Jobst… - Environmental …, 2022 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are a class of pollutants of concern due to their
ubiquitous presence, persistence, and toxicity in aquatic environments. Legacy PFAS …

Endocrine-disruption potential of perfluoroethylcyclohexane sulfonate (PFECHS) in chronically exposed Daphnia magna

M Houde, M Douville, M Giraudo, K Jean… - Environmental …, 2016 - Elsevier
Perfluoroethylcyclohexane sulfonate (PFECHS), mainly used in hydraulic fluids in aircrafts,
is a member of the perfluoroalkyl sulfonate family which includes the regulated …

Cross-species transcriptomics analysis highlights conserved molecular responses to per-and polyfluoroalkyl substances

L Beccacece, F Costa, JP Pascali, FM Giorgi - Toxics, 2023 - mdpi.com
In recent decades, per-and polyfluoroalkyl substances (PFASs) have garnered widespread
public attention due to their persistence in the environment and detrimental effects on the …

Assessing the ecological risks of per‐and polyfluoroalkyl substances: Current state‐of‐the science and a proposed path forward

GT Ankley, P Cureton, RA Hoke… - Environmental …, 2021 - Wiley Online Library
Per‐and poly‐fluoroalkyl substances (PFAS) encompass a large, heterogenous group of
chemicals of potential concern to human health and the environment. Based on information …

Analysis of Sub-Lethal Toxicity of Perfluorooctane Sulfonate (PFOS) to Daphnia magna Using 1H Nuclear Magnetic Resonance-Based Metabolomics

MN Kariuki, EG Nagato, BP Lankadurai, AJ Simpson… - Metabolites, 2017 - mdpi.com
1H nuclear magnetic resonance (NMR)-based metabolomics was used to characterize the
response of Daphnia magna after sub-lethal exposure to perfluorooctane sulfonate (PFOS) …

High-throughput transcriptomic analysis of human primary hepatocyte spheroids exposed to per-and polyfluoroalkyl substances as a platform for relative potency …

A Rowan-Carroll, A Reardon, K Leingartner… - Toxicological …, 2021 - academic.oup.com
Per-and poly-fluoroalkyl substances (PFAS) are widely found in the environment because of
their extensive use and persistence. Although several PFAS are well studied, most lack …

Time-dependent biomolecular responses and bioaccumulation of perfluorooctane sulfonate (PFOS) in Daphnia magna

TY Jeong, MJ Simpson - Comparative Biochemistry and Physiology Part D …, 2020 - Elsevier
Perfluorooctane sulfonate (PFOS) is a persistent pollutant which is potentially harmful and
bioaccumulative to aquatic organisms. To evaluate the regulatory alteration of select …