Integration of induced pluripotent stem cell-derived endothelial cells with polycaprolactone/gelatin-based electrospun scaffolds for enhanced therapeutic …

RP Tan, AHP Chan, K Lennartsson, MM Miravet… - Stem cell research & …, 2018 - Springer
Background Induced pluripotent stem-cell derived endothelial cells (iPSC-ECs) can be
generated from any somatic cell and their iPSC sources possess unlimited self-renewal …

Enhanced therapeutic and long-term dynamic vascularization effects of human pluripotent stem cell–derived endothelial cells encapsulated in a nanomatrix gel

SJ Lee, YD Sohn, A Andukuri, S Kim, J Byun, JW Han… - Circulation, 2017 - Am Heart Assoc
Background: Human pluripotent stem cell (hPSC)–derived endothelial cells (ECs) have
limited clinical utility because of undefined components in the differentiation system and …

Differentiation, evaluation, and application of human induced pluripotent stem cell–derived endothelial cells

Y Lin, CH Gil, MC Yoder - Arteriosclerosis, thrombosis, and …, 2017 - Am Heart Assoc
The emergence of induced pluripotent stem cell (iPSC) technology paves the way to
generate large numbers of patient-specific endothelial cells (ECs) that can be potentially …

A comparison of the pro-angiogenic potential of human induced pluripotent stem cell derived endothelial cells and induced endothelial cells in a murine model of …

ZE Clayton, GSC Yuen, S Sadeghipour… - International journal of …, 2017 - Elsevier
Background Endothelial cells derived from human induced pluripotent stem cells (iPSC-
ECs) promote angiogenesis, and more recently induced endothelial cells (iECs) have been …

[HTML][HTML] 3D culturing of human pluripotent stem cells-derived endothelial cells for vascular regeneration

E Gara, E Zucchelli, A Nemes, Z Jakus, K Ajtay… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Human induced pluripotent stem cell-derived endothelial cells can be candidates
for engineering therapeutic vascular grafts. Methods: Here, we studied the role of three …

[HTML][HTML] Induced pluripotent stem cell–derived endothelial cells: overview, current advances, applications, and future directions

S Jang, AC de l'Hortet, A Soto-Gutierrez - The American Journal of …, 2019 - Elsevier
Endothelial cells are prevalent in our bodies and serve multiple functions. By lining the
vasculature, they provide a barrier to tissues and facilitate the transport of molecules and …

Generation of human pluripotent stem cell-derived endothelial cells and their therapeutic utility

SJ Lee, KH Kim, Y Yoon - Current cardiology reports, 2018 - Springer
Abstract Purpose of Review Human pluripotent stem cell-derived endothelial cells (hPSC-
ECs) emerged as an important source of cells for cardiovascular regeneration. This review …

Evaluating the potential of endothelial cells derived from human induced pluripotent stem cells to form microvascular networks in 3D cultures

JR Bezenah, YP Kong, AJ Putnam - Scientific reports, 2018 - nature.com
A major translational challenge in the fields of therapeutic angiogenesis and regenerative
medicine is the need to create functional microvasculature. The purpose of this study was to …

Induced pluripotent stem cells as vasculature forming entities

A Palladino, I Mavaro, C Pizzoleo, E De Felice… - Journal of Clinical …, 2019 - mdpi.com
Tissue engineering (TE) pursues the ambitious goal to heal damaged tissues. One of the
most successful TE approaches relies on the use of scaffolds specifically designed and …

Derivation and characterization of endothelial cells from porcine induced pluripotent stem cells

Y Yu, X Li, Y Li, R Wei, H Li, Z Liu, Y Zhang - International Journal of …, 2022 - mdpi.com
Although the study on the regulatory mechanism of endothelial differentiation from the
perspective of development provides references for endothelial cell (EC) derivation from …