Intratumoral heterogeneity of ERBB2 amplification and HER2 expression in micropapillary urothelial carcinoma
S Isharwal, H Huang, G Nanjangud, F Audenet… - Human pathology, 2018 - Elsevier
Micropapillary urothelial carcinoma (MPUC) is a rare but an aggressive variant of urothelial
carcinoma. MPUC has been shown to commonly exhibit ERBB2 amplification and HER2 …
carcinoma. MPUC has been shown to commonly exhibit ERBB2 amplification and HER2 …
Micropapillary urothelial carcinoma: evaluation of HER2 status and immunohistochemical characterization of the molecular subtype
U Zinnall, V Weyerer, E Compérat, P Camparo… - Human pathology, 2018 - Elsevier
Comprehensive molecular analyses of urothelial bladder cancer (UBC) have defined distinct
subtypes with potential therapeutic implications. In this study, we focused on micropapillary …
subtypes with potential therapeutic implications. In this study, we focused on micropapillary …
Clinicopathological review of micropapillary urothelial carcinoma
D Kumar, AJ Adeniran - Current Oncology Reports, 2022 - Springer
Abstract Purpose of Review This review will discuss micropapillary urothelial carcinoma with
respect to biology, histopathologic characteristics, genetic and molecular features …
respect to biology, histopathologic characteristics, genetic and molecular features …
Outcome of patients with micropapillary urothelial carcinoma following radical cystectomy: ERBB2 (HER2) amplification identifies patients with poor outcome
SA Schneider, WR Sukov, I Frank, SA Boorjian… - Modern …, 2014 - nature.com
Micropapillary urothelial carcinoma exhibits amplification of the human epidermal growth
factor receptor, ERBB2 (HER2), and overexpression of the ERBB2 protein product. The …
factor receptor, ERBB2 (HER2), and overexpression of the ERBB2 protein product. The …
Invasive micropapillary urothelial carcinoma of the bladder
A Lopez-Beltran, R Montironi, A Blanca, L Cheng - Human pathology, 2010 - Elsevier
In this report, we present the clinicopathologic features of 13 cases of the invasive
micropapillary variant of urothelial carcinoma. This is a rare and aggressive variant of …
micropapillary variant of urothelial carcinoma. This is a rare and aggressive variant of …
A High Frequency of Activating Extracellular Domain ERBB2 (HER2) Mutation in Micropapillary Urothelial Carcinoma
JS Ross, K Wang, LM Gay, RN Al-Rohil, T Nazeer… - Clinical Cancer …, 2014 - AACR
Purpose: Micropapillary urothelial carcinoma (MPUC) is a rare and aggressive form of
bladder cancer. We conducted genomic analyses [next-generation sequencing (NGS)] of …
bladder cancer. We conducted genomic analyses [next-generation sequencing (NGS)] of …
Micropapillary variant of urothelial carcinoma of the urinary bladder; a clinicopathological and immunohistochemical study
H Samaratunga, K Khoo - Histopathology, 2004 - Wiley Online Library
Aims: To investigate whether prognosis in micropapillary urothelial carcinoma is related to
the proportion of the micropapillary component (MPC), and to identify the …
the proportion of the micropapillary component (MPC), and to identify the …
Micropapillary urothelial carcinoma of urinary bladder displays immunophenotypic features of luminal and p53-like subtypes and is not a variant of adenocarcinoma
Y Yang, HZ Kaimakliotis, SR Williamson… - … Oncology: Seminars and …, 2020 - Elsevier
Objectives Micropapillary urothelial carcinoma of the urinary bladder (MPUC) is a rare
variant of urothelial carcinoma which has aggressive clinical characteristics. The objective is …
variant of urothelial carcinoma which has aggressive clinical characteristics. The objective is …
Human epidermal growth factor receptor 2 overexpression in micropapillary and other variants of urothelial carcinoma
K Behzatoğlu, K Yörükoğlu, H Demir, N Bal - European Urology Focus, 2018 - Elsevier
Background Human epidermal growth factor receptor 2 (HER2) protein overexpression or
gene amplification has been shown in urothelial bladder cancer. This could be helpful when …
gene amplification has been shown in urothelial bladder cancer. This could be helpful when …
[HTML][HTML] HER2 gene amplification occurs frequently in the micropapillary variant of urothelial carcinoma: analysis by dual-color in situ hybridization
Human epidermal growth factor receptor-2 (HER2) is a well-recognized growth-promoting
factor in cancer, although its application to urothelial carcinoma has been limited because of …
factor in cancer, although its application to urothelial carcinoma has been limited because of …
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- erbb2 amplification intratumoral heterogeneity
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- her2 expression intratumoral heterogeneity
- immunophenotypic features urothelial carcinoma
- dual color urothelial carcinoma
- clinicopathological analysis urothelial carcinoma
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