Leptin is an important regulator of basal metabolism and food intake, with a pivotal role in
obesity. Leptin exerts many different actions on various tissues and systems, including …

Obesity, defined as the abnormal or excessive expansion of white adipose tissue, has
reached pandemic proportions and is recognized as an important health concern since it is …

Leptin is an obesity-associated adipokine that is known to regulate energy metabolism and
reproduction and to control appetite via the leptin receptor. Recent work has identified …

Over the past decades, obesity has grown to epidemic proportions worldwide. It has been
associated with an increased risk for different types of cancer. In addition, obesity has been …

Leptin is a peptide hormone, mainly known for its role as a mediator of adipose tissue
endocrine functions, such as appetite control and energy homeostasis. In addition, leptin …

The adipocyte-released hormone-like cytokine/adipokine leptin behaves differently in
obesity compared to its functions in the normal healthy state. In obese individuals, elevated …

The discovery of the archetypal adipocytokine leptin and how it regulates energy
homeostasis have represented breakthroughs in our understanding of the endocrine …

Leptin is a peptide hormone that has been characterized as the ligand of leptin receptor
(LEPR). The observation of leptin secretion and leptin receptor expression beyond the …

The prevalence of obesity has markedly increased over the past two decades, especially in
the industrialized countries. While the impact of excess body weight on the development of …

Significant correlations between obesity and incidence of various cancers have been
reported. Obesity, considered a mild inflammatory process, is characterized by a high level …