Asthma is a complex disease of the respiratory tract associated with chronic inflammation in
which an intricate network of cells and cellular factors plays a major role. Asthma is one of …

Asthma is a common inflammatory airway disease for which the most commonly used
controller medications are inhaled corticosteroids (ICS). Asthma control is difficult to achieve …

Inhaled corticosteroids are recommended first‐line therapy for persistent asthma of all
severities; however, oropharyngeal and systemic adverse events can be a concern. Inhaled …

Background Inhaled corticosteroids (ICSs) reduce local airway inflammation, which is an
underlying cause of asthma symptoms. However, potential systemic side effects associated …

Background: Inhaled corticosteroids (ICS) are recommended therapy for persistent asthma,
although side effects can limit appropriate use. Ciclesonide, a novel ICS, is activated in the …

BACKGROUND: Despite their proven efficacy in the treatment and prevention of asthma
exacerbations, current inhaled corticosteroids carry safety concerns, especially adrenal …

The pharmacokinetic and pharmacodynamic effects of inhaled corticosteroids (ICS) have
shaped the efficacy and safety of these agents in the treatment of asthma. Important …

The study addressed the question whether the novel inhaled prodrug corticosteroid
ciclesonide is equally effective when inhaled in the morning compared to the evening. For …

Asthma is a chronic inflammatory disease characterized by symptoms of cough, dyspnea,
chest tightness, and wheeze. Inhaled corticosteroids (ICS) have been recommended as …

Background Ciclesonide is a novel inhaled corticosteroid developed for the treatment of
asthma. Objective To investigate the extent of oral absorption and bioavailability of …