The revitalization of antimicrobial peptides in the resistance era

Y Liu, J Shi, Z Tong, Y Jia, B Yang, Z Wang - Pharmacological Research, 2021 - Elsevier
The antibiotic resistance crisis is becoming incredibly thorny due to the indiscriminate
employment of antibiotics in agriculture and aquaculture, such as growth promoters, and the …

Antimicrobial peptides under clinical investigation

HB Koo, J Seo - Peptide Science, 2019 - Wiley Online Library
Overuse of conventional antibiotics as well as the slow pace of new antibiotic drug
development leads to antimicrobial resistance (AMR). Because infections with multi‐drug …

Rediscovery of antimicrobial peptides as therapeutic agents

M Ryu, J Park, JH Yeom, M Joo, K Lee - Journal of Microbiology, 2021 - Springer
In recent years, the occurrence of antibiotic-resistant pathogens is increasing rapidly. There
is growing concern as the development of antibiotics is slower than the increase in the …

The development of antimicrobial peptides as an approach to prevention of antibiotic resistance

MM Moghaddam, H Aghamollaei… - … and Research in …, 2015 - journals.lww.com
In recent years, the widespread use of conventional antibiotics has led to many microbial
pathogens becoming resistant to these antibiotics. Therefore, the development of novel and …

Research advances of antimicrobial peptides and applications in food industry and agriculture

S Meng, H Xu, F Wang - Current Protein and Peptide Science, 2010 - ingentaconnect.com
Antimicrobial peptides (AMPs) are produced by a wide range of organisms and serve as
their natural defenses against infection caused by bacteria, viruses and fungi. Because of …

Exploring the arsenal of antimicrobial peptides: Mechanisms, diversity, and applications

A Savitskaya, J Masso-Silva, I Haddaoui, S Enany - Biochimie, 2023 - Elsevier
Antimicrobial peptides (AMPs) are essential for defence against pathogens in all living
organisms and possessed activities against bacteria, fungi, viruses, parasites and even …

Antimicrobial peptides: the Achilles' heel of antibiotic resistance?

A Lewies, LH Du Plessis, JF Wentzel - Probiotics and antimicrobial …, 2019 - Springer
Antibiotic resistance is an imminent threat to the effective treatment of bacterial infections,
and alternative antibiotic strategies are urgently required. The golden epoch of antibiotics is …

[HTML][HTML] Antimicrobial peptides as anti-infective agents in pre-post-antibiotic era?

T Rončević, J Puizina, A Tossi - International journal of molecular …, 2019 - mdpi.com
Resistance to antibiotics is one of the main current threats to human health and every year
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …

[HTML][HTML] The role of antimicrobial peptides as antimicrobial and antibiofilm agents in tackling the silent pandemic of antimicrobial resistance

BS Lopes, A Hanafiah, R Nachimuthu, S Muthupandian… - Molecules, 2022 - mdpi.com
Just over a million people died globally in 2019 due to antibiotic resistance caused by
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella …

Antimicrobial peptides: sustainable application informed by evolutionary constraints

X Chen, J Han, X Cai, S Wang - Biotechnology Advances, 2022 - Elsevier
The proliferation and global expansion of multidrug-resistant (MDR) bacteria have
deepened the need to develop novel antimicrobials. Antimicrobial peptides (AMPs) are …